钟志远
时间：2026-03-11




个人简介：钟志远，苏州大学特聘教授，药学院院长，国际创新药学院院长，放射医学与辐射防护国家重点实验室靶向放药中心主任。主要从事药物控制释放、肿瘤靶向治疗和免疫治疗研究。在国际主流期刊发表论文320篇，引用2.5万次，H-因子81。授权60多项国家和国际发明专利（转让12项）。入选国家杰出青年基金获得者（结题特优），国家“万人计划”创新领军人才，国家百千万工程人才，美国医学与生物工程院会士。自2014年起连续9年入选中国高被引学者，2018年起连续5年入选全球高被引科学家。享受国务院政府特殊津贴。担任药学TOP期刊Journal of Controlled Release（IF 10.8)邀稿和综述主编。担任Materials Today、Biomacromolecules、ACS Biomaterials Science & Engineering、Materials Today Chemistry、PLoS One等8本国际期刊编委。担任中国生物材料学会生物医用高分子材料分会副主任委员。曾任Biomacromolecules副主编和苏州BioBAY副总裁。荣获美国化学会“生物大分子/大分子青年研究者奖”、德国洪堡基金会“贝塞尔研究奖”、日本控制释放学会 “亚洲药物释放系统突破技术奖”等国际奖励。


  

代表性论文:


  1. S.J. Yue, Z.Z. Zhai,J.N. An, H.L. Sun*,J.Y. Li, C.Z. Zhao, Y. Xu*,Z.Y. Zhong*,Neutrophil/Leukemia-Tropic Dual-Drug Nanomedicine Potentiates the Treatment of Acute Myeloid Leukemia,Adv. Mater.2026, 38, 2512635.

  2. J.K. Guo,J.T. Huang, Z.L. Huangg, J. Sun, Y. Wang,H.J. Tan,D. Hu, C.Deng*, X.L. Zhu*,Z.Y. Zhong*,Persistent and Potent Anticancer Immunity Empowered by Manganese-Coordinated STING-Activating Microgels,Adv. Funct. Mater.2026, 2521279.

  3. C.L. Ye, Y. Zheng, H.L. He, J.L. Ji, L. Liu, Y. Sun, Y.W. Peng, S.Q. Wang, Y. Zhang*,Z.Y. Zhong*,Single-fraction radiotherapy with a bioactive depot of CD39 blockade eradicates malignant tumors,J. Control. Release. 2026, 391, 1145632.

  4. Y. Wang,J.K. Guo,D. Hu,H.J. Tan, W.T. Chen, C.Deng*, X.L. Zhu*,Z.Y. Zhong*,Absorbable microspheres sustaining epirubicin and TLR7 agonist release for transarterial chemo-immuno-embolization in liver tumor,J. Control. Release. 2026, 390, 114576.

  5. F.H. Meng,S.P.  Schwendeman, A. Pego,Z.Y. Zhong*,Celebrating the 80th birthday of professor Jan Feijen,J. Control. Release. 2026, 391, 1145618.

  6. H.J. Tan, J.K. Guo, Y. Wang, W.T. Chen,Z.Y. Zhong*, C.Deng*,Long-Acting In Situ Cancer Vaccines by Oncolytic STING-Activating Microgels,Small. 2025, 21,e03561.

  7. J.K. Guo, J.T. Huang, Z.L.Huang, D. Hu, H.J. Tan, Y. Wang, C.Deng*,X.L. Zhu*,Z.Y. Zhong*,Tumor vessel-adaptable adhesive andabsorbable microspheres for sustainabletransarterial chemoembolization therapy,Nature Commun.2025, 166239.

  8. B. Xu,L.Tao, J.Sun,J.T.Yang, F.H. Meng*,Z.Y. Zhong*,DNA damage repair inhibitors boost targeted radionuclide therapy and immunotherapy of prostate cancer, Apoptosis. 2025,30,2238-2253.

  9. Y.J. Sha, L. Yang, J.J. Jiang, J. Cao, M. Sun, L.C. Yin,Z.Y. Zhong*,F.H. Meng*,Pre-silencing of TNF-α by targeted siRNA delivery mitigates glucocorticoid resistance of dexamethasone in rheumatoid arthritis, J. Control. Release. 2025, 386, 114112.

  10. H. He, X.Y. Dong, L. Cao, Y.J. Sha, Y.P. Sun, S.S. Zhao,F.H. Meng,Z.Y. Zhong*,Oral Microbiota-Regulating and Inflammation-Targeted Polymersome-Hydrogels for RNAi Therapy of Ulcerative Colitis, Bioactive Mater.2025, 53, 32-44.

  11. J.Sun,J.T.Yang,J.K.Guo, B. Xu,L.Tao,X.Y. Zhao, G.L.Wang,F.H. Meng,Z.Y. Zhong*,Naphthalene-containing octreotide radioligand elevates selectivity and radionuclide therapy for somatostatin receptor 2-positive tumor, Colloids Surf. B, Biointerfaces. 2025, 255,114945.

  12. H.L.He,Y.Zheng, J.L. Ji, C.L.Ye, Y.Sun, Y.W. Peng, Y.Zhang*,Z.Y. Zhong*,Liposomal all-trans retinoic acid boosts anti-tumor immunity of radiotherapy via mitigating cancer stemness and remedying tumor microenvironment. J. Control. Release. 2025, 385, 113995.

  13. J.K. Guo, H.J. Tan, W.T. Chen, Y. Wang, W.H. Lin,Z.Y. Zhong*, C.Deng*,Oncolytic microgels with regulated antibody release augment tumor immunotherapy,J. Control. Release. 2025, 385, 114003.

  14. L.L.Liang,Z.Z.Zhai,W.H.Lin,L.Cao, H.L. Sun*,Z.Y. Zhong*,In situ generation of anti-leukemia vaccine by immunogenic dual-drug nanomedicine and polymersomal CpG nanoadjuvant,2025,J. Colloid Interf. Sci,699, 138144.

  15. Y.Zhao,L.Cao,S.S.Zhao, Z.Z. Zhai,X.L.Tang,L.Chen,H.L. Sun*,Z.Y. Zhong*,Polymersomal vincristine-PLK1 inhibitor boosts immunogenic cell death and antitumor immunity, Chem. Eng. J.2025, 58, 164657.

  16. Q.Deng,S.J.Yue,F.T.You,Z.Z.Zhai,H.L. Sun*,L.L.Liang,C.M.Li,L.Yang *;Z.Y. Zhong*,Vincristine/Volasertib polymersome injection enables high-efficiency synergistic treatment of acute lymphoblastic leukemia, Acta Biomaterial.2025,200,641-652.

  17. Z.W.Sun, J.Y. Wang,B.B.Guo,S.S.Zhao,S.Y.Miao,M.Y.Xia,Z.Y. Zhong*,F.H. Meng*,Nano-golden adjuvant-polymersomes empower tumor photothermal-immunotherapy, J. Control. Release. 2025, 385, 113976.

  18. J.Cao,Y.J.Sha,M.Sun, L. Yang,R.K. Lv,L.Cao,Z.Y. Zhong*,F.H. Meng*,Sustained codelivery of heat shock protein peptide and rapamycin via nano-in-hydrogel induces immune tolerance in rheumatoid arthritis, J. Control. Release. 2025, 383, 113842.

  19. P. Zhang, G.H. Cui, T.Z. Wang, X.F. Zhao, X.Y. Wang, R.N. Ye, T.H. Liu*, Y.R. Zheng*,Z.Y. ong*,In situ therapeutic vaccines for leukemia by chemo-nanoadjuvant therapy, J. Control. Release. 2025,383, 113851.

  20. Y. Shi, Y.P. Sun, S.S.Zhao,Z.W.Sun,M.Y.Xia,Z.Y. Zhong*,F.H. Meng*,Intranasal and Intravenous Sequential Administration of Survivin Peptide-CpG Nanovaccines Elicits Potent Immunity Toward Glioblastoma, Adv. Mater.2025,e2420630.

  21. Z.Z.Zhai,C.M.Li, L. Chen,Y.Zhao,X.L.Tang,L.Cao, H.L. Sun*,Z.Y. Zhong*,Antibody-mediated ratiometric delivery of FLT3 and CDK4/6 dual inhibitors for targeted treatment of acute myeloid leukemia, J. Control. Release. 2025, 384, 113934.

  22. S.S.Zhao,Z.W.Sun,M.Y.Xia, B.B. Guo, Y.Y. Qu, J.Y. Wang,Z.Y. Zhong*,F.H. Meng*,Polymersome-enabled brain codelivery of STAT3 siRNA and CpG oligonucleotide boosts chemo-immunotherapy of malignant glioma, J. Control. Release. 2025, 383, 113764.

  23. S.S. Zhao, Y.Y. Qu,Z.W. Sun, S. Zhang, M.Y. Xia, Y. Shi,J.Y. Wang,Y. Wang,Z.Y. Zhong*,F.H. Meng*,Glioblastoma Cell Lysate and Adjuvant Nanovaccines via Strategic Vaccination Completely Regress Established Murine Tumors, Adv. Healthc. Mater.2025,2500911.

  24. M.Y. Xia, X.Y.Zhao,Z.W.Sun,Y. Shi,W.H.Lin,Z.Y. Zhong*,F.H. Meng*,Brain-targeted polymersomes mediating RNAi of STAT3 sensitize glioblastoma to temozolomide and immunotherapy,J. Colloid Interf. Sci, 2025,695,137751.

  25. R.N. Ye, Q.Z. Ren,L.Chang,S.Q.Zhang,C.Deng,L.Cao,M.Shi,B.Lou,F.H.Meng,S.Du,K.Y.Ren,X.J.Piao,C.C.Xu,Z.Y. Zhong*,Administration route-commended concise organ-selective mRNA transfection (ACCOST) by cyclic disulfide-primed short polyethylenimine,Nano Today. 2025, 63, 102741.

  26. J.Sun,J.T.Yang,J.K.Guo,L.Tao, B. Xu,G.L.Wang*,F.H. Meng,Z.Y. Zhong*,Dual-targeted alpha therapy mitigates prostate cancer and boosts immune checkpoint blockade therapy, J. Control. Release2025, 382, 113686.

  27. Y.Y.Qu,B.B.Guo,S.S.Zhao,J.Sun,J.Cao,M.Y.Xia,Z.Y. Zhong*,F.H. Meng*,Photothermal treatment of prostate tumor with micellar indocyanine green and napabucasin to co-ablate cancer cells and cancer stem cells, J. Control. Release. 2025, 382, 113704.

  28. Y.Y. Zhang,X.F.Zhao,X. Wang, S.Y. Wang,Z.Y. Zhong*, C.Deng*,Polypeptide nanomicelles co-deliver PLK1 and BCL-2/xL inhibitors for synergetic therapy of brain tumor,Nano Today. 2025, 62, 102712.

  29. H.L.He,L.Liu,Y.Zheng, J.L. Ji, L. Cao, C.L.Ye, Y.Sun, Y.Zhang*,Z.Y. Zhong*,Tumor-Adhesive Chitosan-Derived Multi-Immune Agonist Unleashes Strong and Durable Anti-Cancer Immunity. Adv. Sci.2025,e2414110.

  30. L.Yang,Y.J.Sha, Y.S. Wei,L.C.Yin,Z.Y. Zhong*,F.H. Meng*,Inflammation-targeted vesicles for co-delivery of methotrexate and TNF-alpha siRNA to alleviate collagen-induced arthritis,Acta Biomaterialia. 2025,195,338-349.

  31. X.Y.Zhao,J.P.Shen,H.X.Qi,J.Sun,B.Xu,L.Tao,W.H.Lin*,S.L.Li,Z.Y. Zhong*,Thiophene engineering of near-infrared D-π-A nano-photosensitizers for enhanced multiple phototheranostics and inhibition of tumor metastasis,J. Colloid Interf. Sci, 2025,685,291-303.

  32. J.P. Shen, B. Xu, Y. Zheng, X.Y. Zhao, H.X. Qi, Y.G. Tang, W.H. Lin*, S.L. Li*,Z.Y. Zhong*,Near-Infrared Light-Responsive Immunomodulator Prodrugs Rejuvenating Immune Microenvironment for “Cold” Tumor Photoimmunotherapy,Angew. Chem. Int. Ed.2025,e202425309.

  33. S.Q. Wang*,Z.Y. Zhong*,Integrating targeting and drug retention: A promising approach for cancer treatment, J. Control. Release. 2025,378, 247-249.

  34. X.F.Zhao, Y.Y. Zhang, X. Wang, Z.M. Fu,C.Deng*,Z.Y. Zhong*,Multivalent ionizable lipid-polypeptides for tumor-confined mRNA transfection,Bioactive Mater.2025, 46, 423-433.

  35. Y.Sun, L.Liu,H.L.He,G.H.Cui,Y.Zheng,C.L.Ye,L.P.Qu,Y.P.Sun, J.L. Ji,T.Lammers,Y.Zhang*,Z.Y. Zhong*,Co-activating STING-TLR9 pathways promotes radiotherapy-induced cancer vaccination. J. Control. Release. 2025,379, 327-343.

  36. Y.P. Sun, G.H. Cui,Y. Shi, B. Xu, L.P. Qu, F.H. Meng, S.Q. Wang*,Z.Y. Zhong*,Peptide Antigen-Surfaced TLR9-Adjuvanting Nanovaccines as a Versatile Therapeutic Modality to Eradicate Acute Myeloid Leukemia, Adv. Funct. Mater.2025,2416147.

  37. H.L. Sun,Z.Y. Zhong*,Bioresponsive Polymeric Nanoparticles: From Design, Targeted Therapy to Cancer Immunotherapy,Biomacromolecules. 2024,26,33-42.

  38. R. Huang,H. Du,L. Cheng,N.Zhao,P.Z. Zhang,F.H. Meng*,Z.Y. Zhong*,Targeted Delivery of siRNA-Gemcitabine Oligonucleotide Chimeras for High-Efficacy Synergistic Treatment of Pancreatic Cancer, Chem. Mater.2024,36,11881-11891.

  39. G.H. Cui, Y.P. Sun, S.Q. Wang, F.H. Meng,Z.Y. Zhong*,Muramyl Dipeptide-Presenting Polymersomes as Artificial Nanobacteria to Boost Systemic Antitumor Immunity,ACS Appl. Mater. Interfaces,2024,16,61655-61663.

  40. Y.Zhang,L.Liu,H.L.He,Y.Sun,Z.Y. Zhong*,Dual and multi-immune activation strategies for emerging cancer immunotherapy, Mater.Today2024,80,406-428.

  41. Z.Y. Huangfu, J.T. Yang,J.Sun,B.Xu, L. Tao,J.Wu,F.Wang*,G.L.Wang*, F.H. Meng,Z.Y. Zhong*,PSMA and Sigma-1 receptor dual-targeted peptide mediates superior radionuclide imaging and therapy of prostate cancer, J.Control. Release2024,375,767-775.

  42. L.P. Qu, G.H. Cui, Y.P. Sun, R.N. Ye, Y. Sun, F.H. Meng, S.Q. Wang*,Z.Y. Zhong*,A Biomimetic Autophagosomes-Based Nanovaccine Boosts Anticancer Immunity, Adv. Mater.2024,e2409590.

  43. P.Zhang,T.Z.Wang,G.H.Cui,R.N.Ye,W.J.Wan,T.H.Liu*,Y.R.Zheng*,Z.Y. Zhong*,Systemic Multifunctional Nanovaccines for Potent Personalized Immunotherapy of Acute Myeloid Leukemia, Adv. Mater.2024,e2407189.

  44. J.Y. Wang, B.B. Guo, Z.W. Sun, S.S. Zhao, L. Cao,Z.Y. Zhong*,F.H. Meng*,Polymersomal Poly(I:C) Self-Magnifies Antitumor Immunity by Inducing Immunogenic Cell Death and Systemic Immune Activation, Adv. Healthc. Mater.2024,2400784.

  45. G.X. Ma, D. Braatz, P. Tang, Y. Yang, E. Quaas, K. Ludwig, N. Ma, H.L. Sun,Z.Y. Zhong*,Haag, R*,Polyglycerol-Shelled Reduction-Sensitive Polymersome for DM1 Delivery to HER-2-Positive Breast Cancer, Biomacromolecules2024,25,4440-4448.

  46. J.K. Yang, P. Zhang, Y.M. Mao, R. Chen, R. Cheng*, J.Y. Li, H.L. Sun*, C. Deng,Z.Y. Zhong*,CXCR4-Mediated Codelivery of FLT3 and BCL-2 Inhibitors for Enhanced Targeted Combination Therapy of FLT3-ITD Acute Myeloid Leukemia, Biomacromolecules2024,25,4569–4580.

  47. Y.Y. Dong, F.T. You, Y.F. Zhang, H.L. Sun*, R. Cheng, S.S. Zhao, L. Yang,Z.Y. Zhong*,CD7 Nanobody-Based Immuno-Nanotoxin for Targeted Treatment of T-Cell Acute Lymphoblastic Leukemia,ACS Appl. Nano Mater.2024,7,7195-7202.

  48. G.H. Cui, Y.P. Sun, L.P. Qu, C. Shen, Y. Sun, F.H. Meng, Y.R. Zheng*,Z.Y. Zhong*, Uplifting Anti-tumor Immunotherapy with Lymph Node-targeted and Ratio-controlled Co-delivery of Tumor Cell Lysate and Adjuvant, Adv. Healthc. Mater.2024,2303690.

  49. S.J. Yue,J.N. An,Y.F. Zhang, J.Y.Li, C.Z.Zhao,J.Y. Liu, L.L. Liang, H.L. Sun*, Y. Xu*,Z.Y. Zhong*, Exogenous Antigen Upregulation Empowers Antibody Targeted Nanochemotherapy of Leukemia,Adv. Mater. 2023,2209984.

  50. T.Lammers*,Z.Y. Zhong*,Major revision of reviews and invited content,J. Control. Release 2023, 362,726-727.

  51. R.Huang,H.Du,L.Cheng,P.Z.Zhang, F.H. Meng*, Z.Y. Zhong*,Targeted nanodelivery of siRNA against KRAS G12D inhibits pancreatic cancer,Acta Biomaterialia2023,168, 529-539.

  52. R.Huang, F.F. Wang,H.Fu,X.M.Qi,G.Z.Xing,J.Ren*,L.Cheng, F.H. Meng*, Z.Y. Zhong*,Bioresponsive Chimaeric Polymersomes Mediate Sustained and Liver-Specific siRNA Transfection In Vivo,Biomacromolecules2023, 24, 5353-5363.

  53. R.Chen,J.K.Yang,Y.M.Mao,X.F.Zhao,R.Cheng*,C.Deng*,Z.Y. Zhong*,Antibody-Mediated Nanodrug of Proteasome Inhibitor Carfilzomib Boosts the Treatment of Multiple Myeloma,Biomacromolecules2023, 24, 5371-5380.

  54. Q. Yuan, D.Y. Fan, Y.F. Zhang, S.J. Yue, R.Cheng,Z.Y. Zhong*,H.L. Sun*,CD38-selective immuno-nano-DM1 conjugates for depleting multiple myeloma,Biomater.Sci.2023, 11,4985-4994.

  55. J.W. Du, S.J. Yue, C.M. Li, J.Y. Li, S.S. Zhao, Y.Y. Dong, Y.F. Zhang,R.Cheng, H.L. Sun*,Z.Y. Zhong*, Exogenous CD38 upregulation enables high-efficacy dually cascade targeted molecular therapy of leukemia,Nano Today 2023,50, 101872.

  56. W.C. Yan, B.B. Guo, Z. Wang a, J.T. Yang,Z.Y. Zhong*,F.H. Meng*, RGD-directed 24 nm micellar docetaxel enables elevated tumor-liver ratio, deep tumor penetration and potent suppression of solid tumors,J. Control. Release 2023, 360, 304-315.

  57. Y.J. Li, X.Y. Li, J.M. Yi, Y.J. Cao, Z.H. Qin*,Z.Y. Zhong*, W.J. Yang*,Nanoparticle-Mediated STING Activation for Cancer Immunotherapy, Adv. Healthc. Mater.2023,2300260

  58. M.Y. He, M.Y. Wang, T. Xu, M.Y. Zhang, H.X. Dai, C. Wang*, D.W. Ding*,Z.Y. Zhong*, Reactive oxygen species-powered cancer immunotherapy: Current status and challenges,J. Control. Release 2023,356,623-648.

  59. J.G. Xie, X.F. Zhao, P. Zhang, Y.Y. Zhang, R. Cheng,Z.Y. Zhong*, C. Deng*, Codelivery of BCL2 and MCL1 Inhibitors Enabled by Phenylboronic Acid-Functionalized Polypeptide Nanovehicles for Synergetic and Potent Therapy of Acute Myeloid Leukemia,Adv. Sci.2023, 10,2204866.

  60. L.Yang,Y.J.Sha,Y.S.Wei,H.H.Fang,J.J.Jiang,L.C.Yin,Z.Y. Zhong*,F.H. Meng*, Mannose-mediated nanodelivery of methotrexate to macrophages augments rheumatoid arthritis therapy,Biomater.Sci.2023, 11,2211-2220.

  61. B.B.Guo,Y.Qu,Y.P.Sun,S.S.Zhao,J.D.Yuan,P.Z.Zhang,Z.Y. Zhong*,F.H. Meng*, Co-delivery of gemcitabine and paclitaxel plus NanoCpG empowers chemoimmunotherapy of postoperative "cold" triple-negative breast cancer,Bioactive Mater.2023, 25, 61-72.

  62. Y.P Sun,Y.J.Sha, G.H. Cui,F.H. Meng*,Z.Y. Zhong*, Lysosomal-mediated drug release and activation for cancer therapy and immunotherapy,Adv. Drug Deliv. Rev. 2023, 192, 114624.

  63. Y.F. Xia,J.N. An,J.Y. Li,W.X. Gu,Y.F. Zhang,S.S. Zhao, C.Z. Zhao, Y. Xu, B. Li,Z.Y. Zhong*,F.H. Meng*, Transferrin-guided intelligent nanovesicles augment the targetability and potency of clinical PLK1 inhibitor to acute myeloid leukemia,Bioactive Mater.2023, 21, 499-510.

  64. J. Sun, Z.Y. Huangfu, J.T. Yang, G.L. Wang*, K. Hu*, M.Y. Gao,Z.Y. Zhong*, Imaging-Guided Targeted Radionuclide Tumor Therapy: From Concept to Clinical Translation,Adv. Drug Deliv. Rev. 2022, 190, 114538.

  65. X.Y.Ji*,Z.Y. Zhong*, External stimuli-responsive gasotransmitter prodrugs: Chemistry and spatiotemporal release,J. Control. Release 2022,351,81-101.

  66. J.J. Jiang, R.X. Wang, L. Yang, Y.J. Sha, S.S. Zhao, D.F. Chen*,Z.Y. Zhong*,F.H. Meng*, IL-11Rα-targeted nanostrategy empowers chemotherapy of relapsed and patient-derived osteosarcoma,J. Control. Release 2022, 350, 460-470.

  67. Z.Wang,B.B.Guo,S.J.Yue,S.S.Zhao,F.H. Meng*,Z.Y. Zhong*,HER-2-mediated nano-delivery of molecular targeted drug potently suppresses orthotopic epithelial ovarian cancer and metastasis,Int. J. Pharm.2022,625, 122126.

  68. J.Y. Liu, L. Zhang, D.X. Zhao, S.J. Yue, H.L. Sun*, C.F. Ni*,Z.Y. Zhong*, Polymersome-stabilized doxorubicin-lipiodol emulsions for high-efficacy chemoembolization therapy,J. Control. Release 2022,350,122-131.

  69. Q. Zhang, Y.Y. Liu, Y.C. Fei, J.G. Xie, X.F. Zhao, Z.Y. Zhong*, C. Deng*,Phenylboronic Acid-Functionalized Copolypeptides: Facile Synthesis and Responsive Dual Anticancer Drug Release,Biomacromolecules2022, 23, 2989-2998.

  70. H. Zheng, B.B. Guo, X.Y. Qiu, Y.F. Xia, Y. Qu, L. Cheng*, F.H. Meng*,Z.Y. Zhong*,Polymersome-Mediated Cytosolic Delivery of Cyclic Dinucleotide STING Agonist Enhances Tumor Immunotherapy,Bioactive Mater.2022, 16, 1-11.

  71. Y. Zheng*,Z.Y. Zhong*, Roadmap to next-generation cancer vaccines,J. Control. Release 2022,347, 308-313.

  72. J.J. Wei, D. Wu, Y. Shao, B.B. Guo, J.J. Jiang, J. Chen, J.P.Zhang, F.H. Meng*,Z.Y. Zhong*, ApoE-mediated systemic nanodelivery of granzyme B and CpG for enhanced glioma immunotherapy,J. Control. Release 2022,347,68-77.

  73. B.B. Guo, J.J. Wei, J.Y. Wang, Y.P. Sun,J.D. Yuan,andZ.Y. Zhong*,F.H.Meng*,CD44-targeting hydrophobic phosphorylated gemcitabine prodrug nanotherapeutics augment lung cancer therapy,Acta Biomaterialia 2022, 145,200-209.

  74. W.H. Chen, Q.W. Chen, Q. Chen, C.Y. Cui, S. Duan, Y.Y. Kang, Y. Liu, Y. Liu, W.L. Muhammad, S.Q. Shao, C.Q. Tang, J.Q. Wang, L. Wang, M.H. Xiong, L.C. Yin, K.Zhang, Z.Z. Zhang, X. Zhen, J. Feng, C.Y. Gao, Z. Gu, C.L. He, J. Ji, X.Q. Jiang, W.Q. Liu, Z. Liu, H.S. Peng, Y.Q. Shen, L.Q. Shi, X.M. Sun, H. Wang, J. Wang, H.H. Xiao, F.J. Xu, Z.Y. Zhong, X.Z. Zhang, X.S. Chen,Biomedical polymers: synthesis, properties, and applications,Sci. China Chem.2022, 65, 1010-1075.

  75. J.J. Wei, D. Wu, S.S. Zhao, Y. Shao, Y.F. Xia, F.H. Meng*, D.W. Ni, X.Y. Qiu,J.P. Zhang, J. Chen*, andZ.Y. Zhong*,Immunotherapy of Malignant Glioma by Non-Invasive Administration of TLR9 Agonist CpG Nano-immunoadjuvant,Adv. Sci.2022, 9,2103689.

  76. H.H. Fang, Y.J. Sha, L. Yang, J.J. Jiang, L.C. Yin, J.Y. Li, B. Li,B. Klumperman,Z.Y. Zhong*, and F.H. Meng*,Macrophage-Targeted Hydroxychloroquine Nanotherapeutics for Rheumatoid Arthritis Therapy,ACS Appl. Mater. Interfaces2022, 14, 8824-8837.

  77. S.J.Yue, Y.F. Zhang, Y.H. Wei, R. Haag, H.L. Sun*, and Z.Y. Zhong*,Cetuximab-Polymersome-Mertansine Nanodrug for Potent and Targeted Therapy of EGFR-Positive Cancers,Biomacromolecules2022, 23, 100-111.

  78. Y.F. Zhang,J.N. An, Y. Shao, N. Yu,S.J.Yue, H.L. Sun*,J.B. Zhang, W.X. Gu, Y.F. Xia, J.P. Zhang, Y. Xu*, and Z.Y. Zhong*,CD38-Directed Vincristine Nanotherapy for Acute Lymphoblastic Leukemia, Biomacromolecules2022, 23, 377-387.

  79. Z.Wang,S.S.Zhao,F.H.Meng*,J.D. Yuan,andZ.Y. Zhong*,Folate-mediated targeted PLK1 inhibition therapy for ovarian cancer: A comparative study of molecular inhibitors and siRNA therapeutics,Acta Biomaterialia 2022, 138, 443-452.

  80. X.Y.Qiu, Y.Qu, B.B.Guo, H.Zheng,F.H.Meng*, andZ.Y. Zhong*, Micellar paclitaxel boosts ICD and chemo-immunotherapy of metastatic triple negative breast cancer,J. Control. Release 2022,341,498-510.

  81. Y.F. Zhang, S.J. Yue, H.L. Sun*, R. Haag, Z.Y. Zhong*,An intelligent cell-selective polymersome-DM1 nanotoxin toward triple negative breast cancer,J. Control. Release2021,340, 331-341.

  82. Z.H. Zhu,M.R. Wu,J. Sun,Z.Y Huangfu,L.L. Yin,W.P. Yong,J. Sun,G.L. Wang*,F.H. Meng,Z.Y. Zhong*,Redox-sensitive iodinated polymersomes carrying histone deacetylase inhibitor as a dual-functional nano-radiosensitizer for enhanced radiotherapy of breast cancer,Drug Deliv.2021,28, 2301-2309

  83. J.J. Wei, Y.F. Xia, F.H. Meng*, D.W. Ni, X.Y. Qiu,Z.Y. Zhong*,Small, Smart, and LDLR-Specific Micelles Augment Sorafenib Therapy of Glioblastoma,Biomacromolecules2021,22, 4814-4822.

  84. Z. Wang, F.H. Meng, andZ.Y. Zhong*, Emerging targeted drug delivery strategies toward ovarian cancer,Adv. Drug Deliv. Rev. 2021,178,113969

  85. Z.Q. Zhang, Q. Zhang, J.G. Xie,Z.Y. Zhong*, C. Deng*, Enzyme-responsive micellar JQ1 induces enhanced BET proteins inhibition and immunotherapy of malignant tumor,Biomater. Sci.2021,9, 6915-6926

  86. N. Yu, Y.F. Zhang, J.Y.Li, W.X. Gu, S.J. Yue, B. Li,F.H.Meng, H.L. Sun*,R. Haag, J.D. Yuan,andZ.Y. Zhong*,Daratumumab Immunopolymersome-Enabled Safe and CD38-Targeted Chemotherapy and Depletion of Multiple Myeloma,Adv. Mater.2021,33, 2007787.

  87. S.P. Cao,Y.F.Xia,J.X. Shao,B.B. Guo,Y.Y.Dong,I.A. B. Pijpers,Z.Y. Zhong,F.H. Meng*,L.K.E.A. Abdelmohsen,D.S. Williams*, and J. C.M. van Hest*, Biodegradable Polymersomes with Structure Inherent Fluorescence and Targeting Capacity for Enhanced Photo-Dynamic Therapy,Angew. Chem.Int. Ed.2021, 60,17629-17637.

  88. Y.H. Wei, Y.P. Sun, J.J. Wei, X.Y. Qiu, F.H. Meng*, G. Storm*, J.D. Yuan, Z.Y. Zhong*, Selective transferrin coating as a facile strategy to fabricate BBB-permeable and targeted vesicles for potent RNAi therapy of brain metastatic breast cancer in vivo,J. Control. Release2021,337,521-529.

  89. W.X. Gu, R.B. Qu,F.H.Meng*,J.L.M. Cornelissen*,andZ.Y. Zhong*,Polymeric Nanomedicines Targeting Hematological Malignancies,J. Control. Release 2021,337, 571-588.

  90. Y.F. Xia, J.J. Wei, S.S. Zhao, B.B. Guo,F.H.Meng*, B. Klumperman,andZ.Y. Zhong*,Systemic administration of polymersomal oncolytic peptide LTX-315 combining with CpG adjuvant and anti-PD-1 antibody boosts immunotherapy of melanoma,J. Control. Release 2021,336, 262-273.

  91. J. Ouyang, Y. Jiang, C. Deng, Z.Y. Zhong*, andQ. Lan*,Doxorubicin Delivered via ApoE-Directed Reduction-Sensitive Polymersomes Potently Inhibit Orthotopic Human Glioblastoma Xenografts in Nude Mice,Int. J. Nanomed.2021, 16,4105-4115.

  92. Z.Y. Zhong*, Controlled delivery systems are the cornerstone of advanced therapies and vaccines: An Asian perspective,J. Control. Release2021,334, 34-36.

  93. Z.Wang,S.S.Zhao,W.X. Gu,Y.Y. Dong,F.H.Meng*,J.D. Yuan,andZ.Y. Zhong*,α3 integrin-binding peptide-functionalized polymersomes loaded with volasertib for dually-targeted molecular therapy for ovarian cancer,Acta Biomaterialia 2021, 124, 348-357.

  94. J. Zhang,X.X. Wang, L. Cheng*, J.D. Yuan andZ.Y. Zhong*, SP94 Peptide Mediating Highly Specific and Efficacious Delivery of Polymersomal Doxorubicin Hydrochloride to Hepatocellular Carcinoma in Vivo,Colloids Surf. B: Biointerfaces2021, 197,111399

  95. Q.Y. Fan, Y.Y. Liu, G.H. Cui,Z.Y. Zhong*,andC. Deng*,Brain delivery of Plk1 inhibitor via chimaeric polypeptide polymersomes for safe and superb treatment of orthotopic glioblastoma,J. Control. Release 2021,329, 1139-1149.

  96. W.X. Gu,T.H. Liu, D.Y. Fan, J.B. Zhang, Y.F. Xia,F.H.Meng*, Y. Xu*, J.L.M. Cornelissen,Z.J. Liu,andZ.Y. Zhong*, A6 peptide-tagged, ultra-small and reduction-sensitive polymersomal vincristine sulfate as a smart and specific treatment for CD44+ acute myeloid leukemia,J. Control. Release 2021,329, 706-716.

  97. W.X. Gu, F.H.Meng*,R. Haag, andZ.Y. Zhong*, Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation,J. Control. Release 2021,329, 676-695.

  98. H.Y. Wang, X.H.Zhang,Y. Zhang*,R. Cheng*,J.D. Yuan,andZ.Y. Zhong*,Systemic Delivery of NAC-1 siRNA by Neuropilin-Targeted Polymersomes Sensitizes Antiangiogenic Therapy of Metastatic Triple Negative Breast Cancer,Biomacromolecules2020,21, 5119-5127.

  99. C. Gao,Q. Cheng, J.W. Wei, C. Sun, S.Y. Lu, C.H.T. Kwong, S.M.Y. Lee,Z.Y. Zhong*, and R.B. Wang*, Bioorthogonal supramolecular cell-conjugation for targeted hitchhiking drug delivery,Mater. Today2020, 40, 9-17.

  100. C. Deng*,Q. Zhang, J.Q. Guo, X.F. Zhao, andZ.Y. Zhong*, Robust and smart polypeptide-based nanomedicines for targeted tumor therapy,Adv. Drug Deliv. Rev. 2020, 160, 199-211.

  101. C.J. Zhang, X.X. Wang, R. Cheng*, andZ.Y. Zhong*,A6 Peptide-Tagged Core-Disulfide-Crosslinked Micelles for Targeted Delivery of Proteasome Inhibitor Carfilzomib to Multiple Myeloma in Vivo,Biomacromolecules2020, 21, 2049-2059.

  102. C. Zhou, Y.F. Xia, Y.H. Wei, L.Cheng*, J.J. Wei, B.B. Guo, F,H. Meng*, S.P. Cao, J.C.M. van Hest, and Z.Y. Zhong*, GE11 peptide-installed chimaeric polymersomes tailor-made for high-efficiency EGFR-targeted protein therapy of orthotopic hepatocellular carcinoma,Acta Biomaterialia2020, 113, 512-521.

  103. H.L. Sun, andZ.Y. Zhong*, 100thAnniversary of Macromolecular Science Viewpoint: Biological Stimuli-Sensitive Polymer Prodrugs and Nanoparticles for Tumor-Specific Drug Delivery, ACS Macro Lett.2020, 9, 1292-1302.

  104. X.X. Wang,M. Qiu, C. Deng, R. Cheng*, andZ.Y. Zhong*,Targeted and Reduction-Sensitive Crosslinked PLGA Nanotherapeutics for Safer and Enhanced Chemotherapy of Malignant Melanoma,ACS Biomater. Sci. Eng.2020, 6, 2621-2629.

  105. S. Li, M. Qiu, J.K. Guo,Z.Y. Zhong*,and C. Deng*, Coating-Sheddable CD44-Targeted PLGA Nanomedicines Fabricated Using Photo-Click-Crosslinkable Hyaluronic Acid-graft-Tetrazole Conjugate as a Surfactant,Adv. Therapeutics 2020,3, 1900160.

  106. Y. Zou, Y.P. Sun, Y.H. Wei, Y.F. Xia, Z.Y. Huangfu,F.H. Meng*, J. van Hest,J.D. Yuan,andZ.Y. Zhong*,Alfa3beta1 Integrin-Targeting Polymersomal Docetaxel as an Advanced Nanotherapeutics for Non-Small Cell Lung Cancer Treatment,ACS Appl. Mater. Interfaces2020,12,14905-14913.

  107. Y.W. Li, J.J. Wei,Y.H. Wei,L. Cheng*, B.B. Guo,F.H. Meng*,F. Li, andZ.Y. Zhong*, Apolipoprotein E Peptide-Guided Disulfide-Crosslinked Micelles for Targeted Delivery of Sorafenib to Hepatocellular Carcinoma,Biomacromolecules2020, 21, 716-724

  108. H.M. Fang, X.F. Zhao,X.L. Gu,H.L. Sun, R. Cheng,Z.Y. Zhong*,and C. Deng*, CD44-Targeted Multifunctional Nanomedicines Based on a Single-Component Hyaluronic Acid Conjugate with All-Natural Precursors: Construction and Treatment of Metastatic Breast Tumors in Vivo,Biomacromolecules 2020, 21,104-113.

  109. Y.H. Wei, F.H. Meng*, G. Storm,andZ.Y. Zhong*,Transferrin-Binding Peptide Functionalized Polymersomes Mediate Targeted Doxorubicin Delivery to Colorectal Cancer In Vivo,J. Control. Release 2020, 319, 407-415.

  110. Y.N. Zhong,F.H. Meng*,W. Zhang, B. Li, J. van Hest, andZ.Y. Zhong*, CD44-Targeted Vesicles Encapsulating Granzyme B as Artificial Killer Cells for Potent Inhibition of Human Multiple Myeloma in Mice,J. Control. Release2020, 320, 421-430.

  111. Y.Yan,Y.Y. Dong,S.J. Yue, X.Y. Qiu, H.L. Sun*,andZ.Y. Zhong*, Dually Active Targeting Nanomedicines Based on a Direct Conjugate of Two Purely Natural Ligands for Potent Chemotherapy of Ovarian Tumor,ACS Appl. Mater. Interfaces2019, 11, 46548-46557.

  112. H.L. Sun,Z.Y. Zhong*,Biomacromolecules for Emerging Biological and Medical Science and Technology,Biomacromolecules 2019,20, 4241-4242.

  113. H.L. Sun,X.L. Gu,Q. Zhang, H. Xu,Z.Y. Zhong*,and C. Deng*, Cancer Nanomedicines Based on Synthetic Polypeptides,Biomacromolecules 2019,20, 4299-4311.

  114. L. Ding, W.X. Gu, Y.F. Zhang, S.J. Yue, H.L. Sun*, J. Cornelissen,andZ.Y. Zhong*,HER2-Specific Reduction-Sensitive Immunopolymersomes with High Loading of Epirubicin for Targeted Treatment of Ovarian Tumor,Biomacromolecules2019, 20, 3855-3863.

  115. X.L. Gu, Z.H. Zhu, Y.H. Wei, G.L. Wang, F.H. Meng,Z.Y. Zhong*,and C. Deng*, Nano-Agents Based on Poly(ethylene glycol)-b-Poly(L-thyroxine) Block Copolypeptide for Enhanced Dual-Modality Imaging and Targeted Tumor Radiotherapy,Small 2019, 15,1902577.

  116. Y. Zou,Y.H. Wei,J. Bao, F.R. Yao, Z.K. Li, Y.P. Sun,F.H. Meng*, C.H. Hu, G. Storm, andZ.Y. Zhong*, Cyclic RGD-Functionalized and Disulfide-Crosslinked Iodine-Rich Polymersomes as a Robust and Smart Theranostic Agent for Targeted CT Imaging and Chemotherapy of Melanoma,Theranostics2019,9, 8061-8072.

  117. H.L. Sun,Z.Y. Zhong*,and J. Feijen, TheFifthSymposium on Innovative Polymers for Controlled Delivery, September14-17, 2018, Suzhou, China,J. Control. Release2019, 307, 410-412.

  118. W.X. Gu, J.N. An, H. Meng, N. Yu, Y.N. Zhong, F.H.Meng*, Y. Xu*, J.L.M. Cornelissen, andZ.Y. Zhong*, CD44-Specific A6 Short Peptide Boosts Targetability and Anticancer Efficacy of Polymersomal Epirubicin to Orthotopic Human Multiple Myeloma,Adv. Mater.2019, 1904742.

  119. H.Z. Qin, Y. Jiang, J. Zhang,C. Deng*,andZ.Y. Zhong*,Oncoprotein Inhibitor Rigosertib Loaded in ApoE-Targeted Smart Polymersomes Reveals a High Safety and Potency against Human Glioblastoma in Mice,Mol. Pharmaceutics 2019,16,3711-3719.

  120. M. Qiu,J. Ouyang, Y.H. Wei, J. Zhang,Q. Lan,C. Deng*,andZ.Y. Zhong*,Selective cell penetrating peptide-functionalized envelope-type chimaeric lipopepsomes boost systemic RNAi therapy for lung tumor, Adv. Healthcare Mater.2019,1900500.

  121. K. Huang, Y.H. He, Z.H. Zhu, J.K. Guo, G.L. Wang,C. Deng*,andZ.Y. Zhong*,Small, Traceable, Endosome-Disrupting and Bioresponsive Click Nanogels Fabricated via Microfluidics for CD44-Targeted Cytoplasmic Delivery of Therapeutic Proteins,ACS Appl. Mater. Interfaces 2019,11,22171-22180.

  122. J.S. Cao, Y.H. Wei, Y.X. Zhang, G.L. Wang*, X. Ji, andZ.Y.Zhong*,Iodine-rich polymersomes enable versatile SPECT/CT imaging and potent radioisotope therapy for tumor in vivo,ACS Appl. Mater. Interfaces2019,11,18953-18959.

  123. Y.H. Wei, X.L. Gu, L. Cheng*, F.H. Meng*, G. Storm,andZ.Y. Zhong*, Low-toxicity Transferrin-Guided Polymersomal Doxorubicin for Potent Chemotherapy of Orthotopic Hepatocellular Carcinoma in Vivo,Acta Biomaterialia 2019, 92, 196-204.

  124. D. Kuraitis, K. Hosoyama, N.J.R. Blackburn, C. Deng,Z.Y. Zhong*, andE.J. Suuronen*,Functionalization of soft materials for cardiac repair and regeneration,Crit. Rev. Biotechnol.2019, 39,451-468.

  125. X.L. Gu,Y.H. Wei, Q.Y. Fan,H.L. Sun,R. Cheng,Z.Y. Zhong*,and C. Deng*,cRGD-decorated biodegradable polytyrosine nanoparticles for robust encapsulation and targeted delivery of doxorubicin to colorectal cancer in vivo,J. Control. Release 2019,301, 110-118.

  126. N. Rades,K. Achazi,M. Qiu, C. Deng, R. Haag,Z.Y. Zhong*,andK. Licha*,Reductively cleavable polymer-drug conjugates based on dendriticpolyglycerol sulfate and monomethyl auristatin E as anticancer drugs,J. Control. Release 2019,300, 13-21.

  127. X. Xu, W.J. Yang, Y.N. Shi, W.X. Zhang, X. Wang,F.H. Meng, andZ.Y. Zhong*,andL.C. Yin*, Efficient and Targeted Drug/siRNA Co-Delivery Mediated by Reversibly Crosslinked Polymersomes toward Anti-Inflammatory Treatment of Ulcerative Colitis (UC),Nano Res.2019,12,659-667.

  128. J.Chen, H. He, C. Deng*,L.C. Yin,andZ.Y. Zhong*,Saporin-Loaded CD44 and EGFR Dual-Targeted Nanogels for Potent Inhibition of Metastatic Breast Cancer In Vivo,Int. J. Pharmaceutics2019,560, 57-64.

  129. S. Lecommandoux*, H.-A. Klok*,Z.Y. Zhong*,and T.J. Deming*,Future Directionsat the Frontierof Polymer Scienceand Biology,Biomacromolecules2019, 20,1-3.

  130. P.L. Yao, Y.F. Zhang, H. Meng, H.L. Sun*,andZ.Y. Zhong*,Smart polymersomes dually functionalized with cRGD and fusogenic GALA peptides enable specific and high-efficiency cytosolic delivery of apoptotic proteins,Biomacromolecules2019, 20,184-191.

  131. Y. Zou, J.J. Wei, Y.F. Xia,F.H. Meng*, J.D. Yuan, andZ.Y. Zhong*,Targeted chemotherapy for subcutaneous and orthotopic non-small cell lung tumors with cyclic RGD-functionalized and disulfide-crosslinked polymersomal doxorubicin,Signal Transduction and Targeted Therapy2018,3,32.

  132. I.A.B. Pijpers, L.K.E.A. Abdelmohsen, Y.F.Xia, S.P. Cao, D.S. Williams, F.H. Meng*,J.C.M. van Hest*,andZ.Y. Zhong*, Adaptive polymersome and micelle morphologies in anticancer nanomedicine: from design rationale to fabrication and proof-of-concept studies,Adv. Therapeutics2018,1,1800068.

  133. Y. Jiang, J. Zhang*,F.H. Meng, andZ.Y. Zhong*,Apolipoprotein E Peptide-Directed Chimeric Polymersomes Mediate an Ultrahigh-Efficiency Targeted Protein Therapy for Glioblastoma,ACS Nano2018,12, 11070-11079.

  134. L. Cheng, Y. Yang, F.H. Meng*,Z.Y. Zhong*, Protein Nanotherapeutics as an Emerging Modality for Cancer Therapy,Adv. Healthcare Mater.2018, 7,1800685.

  135. M. Qiu,X.X. Wang,H.L. Sun, J. Zhang, C. Deng*,andZ.Y. Zhong*,Cyclic RGD Peptide-Functionalized Polylipopeptide Micelles for Enhanced Loading and Targeted Delivery of Monomethyl Auristatin E,Mol. Pharmaceutics2018,15, 4854-4861.

  136. Y.N. Shi, Y. Jiang, J.S. Cao, W.J. Yang, J. Zhang*,F.H. Meng, andZ.Y. Zhong*,Boosting RNAi therapy for orthotopic glioblastoma with nontoxic brain-targeting chimaeric polymersomes,J. Control. Release2018, 292, 163-171.

  137. H.L. Sun, Y.F. Zhang,andZ.Y. Zhong*,Reduction-Sensitive Polymeric Nanomedicines: An Emerging Multifunctional Platform for Targeted Cancer Therapy,Adv. Drug Deliv. Rev.2018,132, 16-32.

  138. M. Qiu,Z.Q. Zhang, Y.H. Wei,H.L. Sun,F.H. Meng, C. Deng*,andZ.Y. Zhong*,Small-Sized and Robust Chimaeric Lipopepsomes: A Simple and Functional Platform with High Protein Loading for Targeted Intracellular Delivery of Protein Toxin In Vivo,Chem.Mater.2018,30, 6831-6838.

  139. Z.X. Gu, X.X. Wang,R. Cheng*, L. Cheng,andZ.Y. Zhong*,Hyaluronic acid shell and disulfide-crosslinked core micelles for in vivo targeted delivery of bortezomib for the treatment of multiple myeloma,ActaBiomaterialia2018,80, 288-295.

  140. W.J.Yang,Y.H. Wei, J. Zhang,Z.Y. Zhong*,F.H. Meng*,Granzyme B-loaded, cell-selective penetrating and reduction-responsive polymersomes effectively inhibit progression of orthotopic human lung tumor in vivo,J. Control. Release2018, 290, 141-149.

  141. H.L. Sun, Y.Y. Dong, J. Feijen*,andZ.Y. Zhong*,Peptide-Directed Polymeric Nanomedicines for Precision Cancer Therapy,J. Control. Release2018,290, 11-27.

  142. T.J. Deming, H.-A. Klok, S.P. Armes, M.L. Becker, J.A.Champion, E.Y.-X. Chen, S.C. Heilshorn, J.C. M. van Hest,.D.J.Irvine, J.A. Johnson, L.L. Kiessling, H.D. Maynard, M.O.de la Cruz, M.O. Sullivan, M.V. Tirrell, K.S. Anseth, S.Lecommandoux, S.Percec, Z.Y.Zhong, A.-C. Albertsson,Polymers at the Interface with Biology,Biomacromolecules2018,19,3151-3162.

  143. Y. Zou, Y.F. Xia,F.H. Meng*,J. Zhang,andZ.Y. Zhong*,GE11-Directed Functional Polymersomal Doxorubicin as an Advanced Alternative to Clinical Liposomal Formulation for Ovarian Cancer Treatment,Mol. Pharmaceutics2018,15,3664-3671.

  144. S.Xue,X.L. Gu,J. Zhang, H.L. Sun, C. Deng*,andZ.Y. Zhong*,Construction of Small-Sized, Robust and Reduction-Responsive Polypeptide Micelles for High Loading and Targeted Delivery of Chemotherapeutics,Biomacromolecules2018,19, 3586-3593.

  145. T. Chen, M. Qiu,J.Zhang,H.L. Sun,C. Deng*,andZ.Y. Zhong*,Integrated Multifunctional Micelles Co-Self-Assembled from Polypeptides Conjugated with Natural Ferulic Acid and Lipoic Acid for Efficient and Bioresponsive Doxorubicin Delivery,ChemPhysChem2018, 19,2070-2077.

  146. D.C. Huang, H.L. Qian, H.S., Qiao, W. Chen*,J. Feijen, andZ.Y. Zhong*,Bioresponsive Functional Nanogels as An Emerging Platform for Cancer Therapy, Expert Opin. Drug Deliv.2018, 15, 703-716.

  147. Y. Jiang, W.J. Yang, J. Zhang*,F.H. Meng, andZ.Y. Zhong*,Protein Toxin Chaperoned by LRP-1 Targeted Virus-Mimicking Vesicles Induces High-Efficiency Glioblastoma Therapy In Vivo,Adv. Mater.2018,30, 1800316.

  148. H.L. Sun, H.A. Klok*,andZ.Y. Zhong*, Polymers from Nature and for Nature,Biomacromolecules2018,19, 1697-1700.

  149. J.J. Wei, M. Meng, B.B. Guo,Z.Y. Zhong*, andF.H. Meng*,Organocatalytic ring-opening copolymerization of trimethylene carbonate and dithiolane trimethylene carbonate: Impact of organocatalysts on copolymerization kinetics and copolymer microstructures,Biomacromolecules2018,19, 2294-2301.

  150. Y.Q.Zhu, J. Zhang,F.H. Meng,L. Cheng*, J. Feijen*, andZ.Y. Zhong*,Reduction-Responsive Core-Crosslinked Hyaluronic Acid-b-Poly(Trimethylene Carbonate-co-Dithiolane Trimethylene Carbonate) Micelles: Synthesis and CD44-Mediated Potent Delivery of Docetaxel to Triple Negative Breast Tumor In Vivo,J. Mater. Chem. B2018, 6, 3040-3047.

  151. X.L. Gu, M. Qiu, H.L. Sun,J. Zhang,L. Cheng,C. Deng*,andZ.Y. Zhong*,Polytyrosine nanoparticles enable ultra-high loading of doxorubicin and rapidly enzyme-responsive drug release,Biomater.Sci.2018,6, 1526-1534.

  152. W.J.Yang,Y.F. Xia, Y. Fang, F.H. Meng*, J. Zhang, R. Cheng, C. Deng,andZ.Y. Zhong*,Selective Cell Penetrating Peptide-Functionalized Polymersomes Mediate Efficient and Targeted Delivery of Methotrexate Disodium to Human Lung Cancer In Vivo,Adv. Healthcare Mater.2018,7,1701135.

  153. X.X. Wang,R. Cheng*, L. Cheng,andZ.Y. Zhong*,Lipoyl ester terminated star PLGA as a simple and smart material for controlled drug delivery application,Biomacromolecules2018,19, 1368-1373.

  154. Y.Q.Zhu, Y. Jiang,F.H. Meng, C. Deng, R. Cheng,J. Zhang*,J. Feijen*, andZ.Y. Zhong*,Highly efficacious and specific anti-glioma chemotherapy by smart tandem nanomicelles co-functionalized with brain tumor-targeting and cell-penetrating peptides,J. Control. Release2018,278, 1-8.

  155. W.J.Yang,Y.F. Xia, L. Cheng*,J. Zhang,F.H. Meng*,J.D. Yuan,andZ.Y. Zhong*,Lung cancer specific and reduction-responsive chimaeric polymersomes for highly efficient loading of pemetrexed and targeted suppression of lung tumor in vivo,Acta Biomaterialia 2018, 70, 177-185.

  156. Y.Q.Zhu,J. Feijen*, andZ.Y. Zhong*,Dual-TargetedNanomedicines for Enhanced Tumor Treatment,Nano Today2018,18, 65-85.

  157. M. Qiu, H.L. Sun, F.H. Meng, R. Cheng, J. Zhang, C. Deng*,andZ.Y. Zhong*,Lipopepsomes: A novel and robust family of nano-vesicles capable of highly efficient encapsulation and tumor-targeted delivery of doxorubicin hydrochloride in vivo,J. Control. Release2018,272, 107-113.

  158. J. Chen, K. Huang, Q.J. Chen,C. Deng*,J. Zhang,andZ.Y. Zhong*,Tailor-Making Fluorescent Hyaluronic Acid Microgels via Combining Microfluidics and Photoclick Chemistry for Sustained and Localized Delivery of Herceptin in Tumor,ACS Appl. Mater. Interfaces2018,10, 3929-3937.

  159. Y. Zhang, K.Q. Wu, H.L. Sun*, J. Zhang, J.D. Yuan, and Z.Y. Zhong*,Hyaluronic acid-shelled disulfide-crosslinked nano-polymersomes for ultrahigh-efficiency reactive encapsulation and CD44-targeted delivery of mertansine toxin,ACS Appl. Mater. Interfaces2018, 10, 1597-1604.

  160. L.L. Ding,Y. Jiang, J. Zhang*, H.A. Klok, andZ.Y. Zhong*,pH-Sensitive Coiled-Coil Peptide-Crosslinked Hyaluronic Acid Nanogels: Synthesis and Targeted Intracellular Protein Delivery to CD44 Positive Cancer Cells,Biomacromolecules2018, 19, 555-562.

  161. Z.Y. Zhong*,Innovative Polymers for Controlled Release Applications,Biomacromolecules2017, 18, 3652-3653.

  162. Y.N. Zhong, F.H. Meng*,C. Deng,X.L. Mao*,andZ.Y. Zhong*,Targeted Inhibition of Human Hematological Cancers In Vivo by Doxorubicin Encapsulated in Smart Lipoic Acid-Crosslinked Hyaluronic Acid Nanoparticles,Drug Delivery2017,24, 1482-1490.

  163. Y.Q.Zhu, J. Zhang,F.H. Meng, C. Deng, R. Cheng, J. Feijen*, andZ.Y. Zhong*,cRGD/TAT dual-ligand reversibly crosslinked micelles loaded with docetaxel penetrate deeply into tumor tissue and show high antitumor efficacy in vivo,ACS Appl. Mater. Interfaces2017,9,35651-35663.

  164. W.J.Yang,Y.F. Xia, Y. Zou, F.H. Meng*, J. Zhang,andZ.Y. Zhong*,Bioresponsive chimaeric nano-polymersomes enable targeted and efficacious protein therapy for human lung cancers in vivo,Chem. Mater.2017, 29, 8757-8765.

  165. Y. Fang, W.J.Yang,L. Cheng*, F.H. Meng*, J. Zhang,andZ.Y. Zhong*,EGFR-targeted multifunctional polymersomal doxorubicin induces selective and potent suppression of orthotopic human liver cancer in vivo,Acta Biomaterialia 2017, 64, 323-333.

  166. P. Zhong, X.L. Gu,R. Cheng*,C. Deng,F.H. Meng,andZ.Y. Zhong*,αvβ3Integrin-Targeted Micellar Mertansine Prodrug Effectively Inhibits Triple-Negative Breast Cancer In Vivo,Int. J. Nanomed.2017,12, 7913-7921

  167. N.J.R. Blackburn, B. Vulesevic, B. McNeill,C.E. Cimenci, A. Ahmadi,M.G. Gomez,A.Ostojic, Z.Y. Zhong, M. Brownlee,P.J. Beisswenger,R.W. Milne,E.J. Suuronen,Methylglyoxal-derived advanced glycation end productscontribute to negative cardiac remodeling and dysfunction post-myocardial infarction,Basic Res. Cardiol.2017,112,57.

  168. J. Qiu,R. Cheng*, J. Zhang, H.L. Sun,C. Deng,F.H. Meng,andZ.Y. Zhong*,Glutathione-Sensitive Hyaluronic Acid-Mercaptopurine Prodrug Linked via Carbonyl Vinyl Sulfide: A Robust and CD44-Targeted Nanomedicine for Leukemia,Biomacromolecules2017,18, 3207-3214.

  169. H. Meng, Y. Zou, P. Zhong,F.H. Meng*, J. Zhang, R. Cheng, andZ.Y. Zhong*,A Smart Nano-Prodrug Platform with Reactive Drug Loading, Superb Stability and Fast Responsive Drug Release for Targeted Cancer Therapy,Macromol. Biosci.2017, 17, 1600518

  170. Y. Zou,M. Zheng, W.J. Yang, F.H. Meng*, K. Miyata, H.J. Kim, K. Kataoka*,andZ.Y. Zhong*,Virus-Mimicking Chimaeric Polymersome Boosts Targeted Cancer siRNA Therapy in Vivo,Adv. Mater.2017, 29,1703285

  171. M. Qiu, J. Ouyang, H.L. Sun, F.H. Meng, R. Cheng, J. Zhang, L. Cheng, Q. Lan, C. Deng*,andZ.Y. Zhong*,Biodegradable micelles based on poly(ethylene glycol)-b-polylipopeptide copolymer:  A robust and versatile nanoplatform for anticancer drug delivery,ACS Appl. Mater. Interfaces2017,9, 27587-27595.

  172. C.F. Hang, Y. Zou, Y.N. Zhong,Z.Y. Zhong*, andF.H. Meng*,NIR and UV-responsive degradable hyaluronic acid nanogels for CD44-targeted and remotely triggered intracellular doxorubicin delivery,Colloids Surf. B: Biointerfaces2017, 158,547-555.

  173. J. Chen,J. Ouyang, Q.J. Chen, C. Deng*, F.H. Meng, J. Zhang, R. Cheng, Q. Lan,andZ.Y. Zhong*,EGFR and CD44 Dual-Targeted Multifunctional Hyaluronic Acid Nanogels Boost Protein Delivery to Ovarian and Breast Cancers in Vitro and in Vivo,ACS Appl. Mater. Interfaces2017,9, 24140-24147.

  174. K.Q. Wu,R. Cheng*, J. Zhang, F.H. Meng, C. Deng,andZ.Y. Zhong*,Micellar Nanoformulation of Lipophilized Bortezomib: High Drug Loading, Improved Tolerability and Targeted Treatment of Triple Negative Breast Cancer,J. Mater. Chem. B2017, 5, 5658-5667.

  175. Z.Y. Zhong*,and J. Feijen, TheFourthSymposium on Innovative Polymers for Controlled Delivery, September23-26, 2016, Suzhou, China,J. Control. Release2017,259, 1-2.

  176. P. Zhong, M. Qiu, J. Zhang, H.L. Sun,R. Cheng*,C. Deng,F.H. Meng,andZ.Y. Zhong*,cRGD-Installed Docetaxel-Loaded Mertansine Prodrug Micelles: Redox-Triggered Ratiometric Dual Drug Release and Targeted Synergistic Treatment of B16F10 Melanoma,Nanotechnology2017, 28, 295103.

  177. J.T. Wu,C. Deng*, F.H. Meng, J. Zhang, H.L. Sun,andZ.Y. Zhong*,Hyaluronic acid coated PLGA nanoparticulate docetaxel effectively targets andsuppresses orthotopic human lung cancer,J. Control. Release2017,259, 76-82.

  178. P. Zhong, H. Meng, J. Qiu, J. Zhang, H.L. Sun,R. Cheng*,andZ.Y. Zhong*,αvβ3 Integrin-Targeted Reduction-Sensitive Micellar Mertansine Prodrug: Superb Drug Loading, Enhanced Stability, and Effective Inhibition of Melanoma Growth In Vivo,J. Control. Release2017,259, 176-186.

  179. Y. Zou, Y.H. Wei, G.L. Wang,F.H. Meng*, M.Y. Gao, G. Storm, andZ.Y. Zhong*,Nano-Polymersomes with an Ultrahigh Iodine Content for High-Performance X-Ray Computed Tomography Imaging In Vivo,Adv. Mater.2017,29, 1603997.

  180. N. Zhang,Y.F. Xia, Y. Zou,W.J. Yang, J. Zhang,Z.Y. Zhong*,and F.H. Meng*,ATN-161 Peptide Functionalized Reversibly Crosslinked Polymersomes Mediate Targeted Doxorubicin Delivery into Melanoma-Bearing C57BL/6 Mice,Mol. Pharm.2017, 14, 2538-2547.

  181. Y. Fang, Y. Jiang, Y. Zou,F.H. Meng*, J. Zhang, C. Deng,H.L. SunandZ.Y. Zhong*,Targeted glioma chemotherapy by cyclic RGD peptide-functionalized reversibly core-crosslinked multifunctional poly(ethylene glycol)-b-poly(-caprolactone) micelles,Acta Biomaterialia2017,50, 396-406.

  182. Y.Q.Zhu, X.X. Wang, J. Zhang,F.H. Meng, C. Deng, R. Cheng, J. Feijen*, andZ.Y. Zhong*,Exogenous vitamin C boosts the antitumor efficacy of paclitaxel containing reduction-sensitive shell-sheddable micellesin vivo, J. Control. Release2017, 250, 9-19.

  183. J.T. Wu, J. Zhang,C. Deng*, F.H. Meng, R. Cheng,andZ.Y. Zhong*,Robust, Responsive and Targeted PLGA Anticancer Nanomedicines by Combining Reductively Cleavable Surfactant and Covalent Hyaluronic Acid Coating,ACS Appl. Mater. Interfaces2017, 9, 3985-3994.

  184. W. Chen, Y. Zou,Z.Y. Zhong*, and R. Haag *,Cyclo(RGD)-decorated Redox-responsive Nanogels Mediate Targeted Chemotherapy of Integrin Over-expressing Human Glioblastoma In Vivo,Small 2017,13, 1601997.

  185. J. Chen, Y. Zou,C. Deng*, F.H. Meng, J. Zhang,andZ.Y. Zhong*,Multifunctional Click Hyaluronic Acid Nanogels for Targeted Protein Delivery and Effective Cancer Treatment In Vivo,Chem. Mater.2016,28, 8792-8799.

  186. P. Zhong, J. Zhang,C. Deng,R. Cheng*,F.H. Meng,andZ.Y. Zhong*,Glutathione-Sensitive Hyaluronic Acid-SS-Mertansine Prodrug with a High Drug Content: Facile Synthesis and Targeted Breast Tumor Therapy,Biomacromolecules2016, 17, 3602-3608.

  187. Y.N. Zhong,M. Dimde, D. Stöbener,F.H. Meng*,C. Deng,Z.Y. Zhong*,andR. Haag,Micelles with Sheddable Dendritic Polyglycerol Sulfate Shells Show Extraordinary Tumor Targetability and Chemotherapy In Vivo,ACS Appl. Mater. Interfaces2016, 8, 27530-27538.

  188. W.J.Yang,Y. Zou, F.H. Meng*, J. Zhang, R. Cheng, C.Deng,andZ.Y. Zhong*,Efficient and targeted suppression of human lung tumor xenografts in mice with methotrexate sodium encapsulated in all-function-in-one chimaeric polymersomes,Adv. Mater.2016, 28, 8234-8239.

  189. Y.Q.Zhu, X.X. Wang, J. Chen, J. Zhang,F.H. Meng, C. Deng, R. Cheng, J. Feijen*, andZ.Y. Zhong*,Bioresponsive and fluorescent hyaluronic acid-iodixanol nanogels for targeted X-ray computed tomography imaging and chemotherapy of breast tumors, J. Control. Release2016,244, 229-239.

  190. Y. Zou,F.H. Meng*, C. Deng, andZ.Y. Zhong*,Robust, tumor-homing and redox-sensitive polymersomal doxorubicin: A superioralternative to Doxil and Caelyx?J. Control. Release2016, 239, 149-158.

  191. S. Li, J. Zhang,C. Deng*, F.H. Meng, L. Yu,andZ.Y. Zhong*,Redox-sensitive and intrinsically fluorescent photoclick hyaluronic acid nanogels for traceable and targeted delivery of cytochromeC to breast tumor in mice,ACS Appl. Mater. Interfaces2016, 8, 21155-21162

  192. B.F. Sun,C. Deng*,F.H. Meng, J. Zhang, andZ.Y. Zhong*, Robust, active tumor-targeting and fast bioresponsive anticancer nanotherapeutics based on natural endogenous materials,Acta Biomaterialia2016,45, 223-233.

  193. J.T. Wu, J. Zhang,C. Deng*, F.H. Meng,andZ.Y. Zhong*,Vitamin E-Oligo(methyl diglycol L-glutamate) as a Biocompatible and Functional Surfactant for Facile Preparation of Active Tumor-Targeting PLGA Nanoparticles,Biomacromolecules2016,17, 2367-2374

  194. Y. Zou, H. Meng,F.H. Meng*, C. Deng,J. Zhang,andZ.Y. Zhong*,Self-crosslinkable and intracellularly decrosslinkable biodegradable micellar nanoparticles: a robust, simple and multifunctional nanoplatform for high-efficiency targeted cancer chemotherapy,J. Control. Release2016,244, 326-335.

  195. Y.Q.Zhu, J. Zhang*, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, andZ.Y. Zhong*,cRGD-functionalized reduction-sensitive shell-sheddable biodegradable micelles mediate enhanced doxorubicin delivery to human glioma xenografts in vivo, J. Control. Release2016, 233, 29-38.

  196. X.Ma, Z.W. He, F.X. Han,Z.Y. Zhong*, L. Chen, and B. Li*,Preparation of collagen/hydroxyapatite/alendronate hybrid hydrogels as potential scaffolds for bone regeneration,Colloids Surf. B: Biointerfaces2016, 143, 81-87.

  197. X.X. Wang, J. Zhang,R. Cheng*,F.H. Meng,C. Deng,andZ.Y. Zhong*,Facile synthesis of reductively degradable biopolymers using cystamine diisocyanate as a coupling agent,Biomacromolecules2016,17, 882-890.

  198. Y.N. Zhong, K. Goltsche,L. Cheng, F. Xie,F.H. Meng*,C. Deng,Z.Y. Zhong*,andR. Haag,Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo,Biomaterials2016, 84,250-261.

  199. X.Li,W.J. Yang, Y. Zou, F.H. Meng*, C.Deng,andZ.Y. Zhong*,Efficacious delivery of protein drugs to prostate cancer cells by PSMA-targeted pH-responsive chimaeric polymersomes,J. Control. Release2015,220, 704-714.

  200. R. Cheng,F.H. Meng,C. Deng,andZ.Y. Zhong*,Bioresponsive Polymeric Nanotherapeutics for Targeted Cancer Chemotherapy,Nano Today2015,10, 656-670.

  201. S.Y. Liu*, andZ.Y. Zhong*,  Preface -Special Topic: Progress in Synthetic Polymer Chemistry,SCIENCE CHINA Chemistry2015, 58, 1631-1632.

  202. W.T.Lu, X.X. Wang,R. Cheng*,C. Deng,F.H. Meng,andZ.Y. Zhong*,Biocompatible and Bioreducible Micelles Fabricated from Novel α-Amino Acid-Based Poly(disulfide urethane)s: Design, Synthesis and Triggered Doxorubicin Release,Polymer Chemistry2015,6, 6001-6010.

  203. F.S. Huang,R. Cheng*,F.H. Meng,C. Deng,andZ.Y. Zhong*,Micelles Based on Acid Degradable Poly(acetal urethane): Preparation, pH-Sensitivity, and Triggered Intracellular Drug Release,Biomacromolecules2015,16, 2228-2236.

  204. L.Lu, Y. Zou, W.J. Yang,F.H. Meng*,C. Deng, R. Cheng, andZ.Y. Zhong*,Anisamide-Decorated pH-Sensitive Degradable Chimaeric Polymersomes Mediate Potent and Targeted Protein Delivery to Lung Cancer Cells,Biomacromolecules2015,16, 1726-1735

  205. W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, andZ.Y. Zhong*,Facile Construction of Dual-Bioresponsive Biodegradable Micelles with Superior Extracellular Stability and Activated Intracellular Drug Release, J. Control. Release2015, 210, 125-133

  206. Z.Y. Zhong*,Professor Jan Feijen: a Pioneer in Biomedical Polymers and Controlled Drug Release,J. Control. Release2015, 205, 3-6.

  207. Z.Y. Zhong*,and J. Feijen, TheThird Symposium on Innovative Polymers for Controlled Delivery, September 16-19, 2014, Suzhou, China,J. Control. Release2015, 205, 1-2.

  208. H. He, Y.G. Bai, J.H. Wang, Q.R. Deng, L.P. Zhu,F.H. Meng,Z.Y. Zhong*,and L.C. Yin*, Reversibly crosslinked polyplexes enable cancer-targeted gene delivery via self-promoted DNA release and self-diminished toxicity,Biomacromolecules2015,16, 1390-1400.

  209. P.P. Chen,M. Qiu,C. Deng*,F.H. Meng,J. Zhang,R. Cheng, andZ.Y. Zhong*,pH-Responsive Chimaeric Pepsomes Based on Asymmetric Poly(ethylene glycol)-b-Poly(L-leucine)-b-Poly(L-glutamic acid) Triblock Copolymer for Efficient Loading and Active Intracellular  Delivery of Doxorubicin Hydrochloride, Biomacromolecules2015,16, 1322-1330.

  210. J.L.Lv,H.L. Sun, Y. Zou, F.H. Meng*,A.A. Dias, M. Hendriks, J. Feijen,andZ.Y. Zhong*,Reductively Degradable-Amino Acid-Based Poly(ester amide)-Graft-Galactose Copolymers: Facile Synthesis, Self-Assembly, and Hepatoma-Targeting Doxorubicin Delivery,Biomater. Sci.2015,3, 1134-1146.

  211. Y.N. Zhong, J. Zhang, R. Cheng*, C. Deng, F.H. Meng,F. Xie*,andZ.Y. Zhong*,Reversibly Crosslinked Hyaluronic Acid Nanoparticles for Active Targeting and Intelligent Delivery of Doxorubicin to Drug Resistant CD44+ Human Breast Tumor Xenografts,J. Control. Release2015, 205, 144-154.

  212. W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, andZ.Y. Zhong*,Biodegradable Glycopolymer-b-Poly(-caprolactone) Block Copolymer Micelles: Versatile Construction, Tailored Lactose Functionality, and Hepatoma-Targeted Drug Delivery,J. Mater. Chem. B2015, 3, 2308-2317.

  213. H.L. Sun, R. Cheng, C. Deng, F.H. Meng*,A.A. Dias, M. Hendriks, J. Feijen,andZ.Y. Zhong*,Enzymatically and Reductively Degradable-Amino Acid-Based Poly(ester amide)s: Synthesis, Cell Compatibility, and Intracellular Anticancer Drug Delivery,Biomacromolecules2015,16, 597-605.

  214. G.H. Xu,X.L. Wang,C. Deng*,X.M. Teng, E.J. Suuronen, Z.Y. Shen*, andZ.Y. Zhong*, Injectable Biodegradable Hybrid Hydrogels Based on Thiolated Collagen and Oligo(acryloyl carbonate)-Poly(ethylene glycol)-Oligo(acryloyl carbonate) Copolymer for Functional Cardiac Regeneration,Acta Biomaterialia2015,15, 55-64.

  215. N.J.R. Blackburn, T. Sofrenovic, D. Kuraitis, A.Ahmadi, B. McNeill, C. Deng, K.J. Rayner,Z.Y. Zhong, M. Ruel,andE.J. Suuronen*, Timing underpins the benefits associated with injectable collagen biomaterial therapy for the treatment of myocardial infarction,Biomaterials2015, 39,182-192.

  216. W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, andZ.Y. Zhong*,Advanced Drug and Gene Delivery Systems Based on Functional Biodegradable Polycarbonates and Copolymers,J. Control. Release2014, 190, 398-414.

  217. Y.N. Zhong, C. Wang, R. Cheng, L. Cheng,F.H. Meng*, Z. Liu*, andZ.Y. Zhong*,cRGD-Directed, NIR-Responsive and Robust AuNR/PEG-PCL Hybrid Nanoparticles for Targeted Chemotherapy of Glioblastoma In Vivo,J. Control. Release2014,195, 63-71.

  218. Y.N. Zhong,F.H. Meng,C. Deng*, andZ.Y. Zhong*,Ligand-Directed Active Tumor-Targeting Polymeric Nanoparticles for Cancer Chemotherapy,Biomacromolecules2014,15, 1955-1969.

  219. Y. Zou, Y. Song, W.J.Yang, F.H. Meng*, H.Y.Liu, andZ.Y. Zhong*,Galactose-Installed Photo-Crosslinked pH-Sensitive Degradable Micelles for Active Targeting Chemotherapy of Hepatocellular Carcinoma in Mice,J. Control. Release2014, 193, 154-161.

  220. Y.J. Jiang, J. Chen,C. Deng*, E. Suuronen, andZ.Y. Zhong*,Click Hydrogels, Microgels and Nanogels: Emerging Platforms for Drug Delivery and Tissue Engineering,Biomaterials2014,35, 4969-4985.

  221. C. Deng,J.T. Wu,R. Cheng, F.H. Meng,H.A. Klok, andZ.Y. Zhong*,Functional Polypeptide and Hybrid Materials: Precision Synthesis via α-Amino Acid N-Carboxyanhydride Polymerization and Emerging Biomedical Applications,Prog. Polym. Sci.2014, 39, 330-364.

  222. W. Chen,Y. Zou, F.H. Meng, R. Cheng, C. Deng, J. Feijen, andZ.Y. Zhong*,Glyco-Nanoparticles with Sheddable Saccharide Shells: A Unique and Potent Platform for Hepatoma-Targeting Delivery of Anticancer Drugs,Biomacromolecules2014,15, 900-907.

  223. H.L. Sun, F.H. Meng*,R. Cheng, C. Deng, andZ.Y. Zhong*,Reduction and pH Dual-Bioresponsive Crosslinked Polymersomesfor Efficient Intracellular Deliveryof Proteinsand Potent Inductionof Cancer Cell Apoptosis,Acta Biomaterialia2014,10, 2159-2168

  224. F.H. Meng, Y.N. Zhong,R. Cheng, C. Deng, andZ.Y. Zhong*,pH-Sensitive polymericnanoparticles for tumor-targeting doxorubicin delivery: Concept and recent advances,Nanomedicine2014, 9, 487-499. (invited review)

  225. H.L. Sun, F.H. Meng*,R. Cheng, C. Deng, andZ.Y. Zhong*,Reduction-Responsive Polymeric Micelles and Vesicles for Triggered Intracellular Drug Release,Antioxidants & Redox Signaling2014, 21, 755-767. (invited forum article)

  226. W.W. Guo, M. Zheng, Y.N. Zhong,F.H. Meng,C. Deng*, andZ.Y. Zhong*,Poly(ethylene oxide)-graft-methotrexate Macromolecular Drugs Conjugating via Aminopteridine Ring Exhibit Potent Anticancer Activity,Chinese Journal of Chemistry2014, 32,57-65.

  227. Y.N. Zhong, W.J. Yang,H.L. Sun, R. Cheng, F.H. Meng,C. Deng*, andZ.Y. Zhong*,Ligand-Directed Reduction-Sensitive Shell-Sheddable Biodegradable Micelles Actively Deliver Doxorubicin into the Nuclei of Target Cancer Cells,Biomacromolecules2013,14, 3723-3730.

  228. J.R. Zhou,P.P. Chen,C. Deng*,F.H. Meng, R. Cheng, andZ.Y. Zhong*,A Simple and Versatile Synthetic Strategy to Functional Polypeptides via Vinyl Sulfone-Substituted L-Cysteine N-Carboxyanhydride,Macromolecules2013, 46, 6723–6730.

  229. Y.P. Fan, C. Deng*,R. Cheng, F.H. Meng, andZ.Y. Zhong*,In Situ Forming Hydrogels via Catalyst-Free and Bioorthogonal “Tetrazole–Alkene” Photo-Click Chemistry,Biomacromolecules2013,14, 2814-2821.

  230. X.Y. Wang,H.L. Sun, F.H. Meng*,R. Cheng, C. Deng, andZ.Y. Zhong*,Galactose-Decorated Reduction-Sensitive Degradable Chimaeric Polymersomes as a Multifunctional Nanocarrier To Efficiently Chaperone Apoptotic Proteins into Hepatoma Cells,Biomacromolecules2013, 14,2873-2882.

  231. Y.D. Gu, Y.N.Zhong, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*,Acetal-Linked Paclitaxel Prodrug Micellar Nanoparticles as a Versatile and Potent Platform for Cancer Therapy,Biomacromolecules2013, 14, 2772-2780.

  232. Y.N.Zhong,W. Wang,L. Cheng,  F.H. Meng,Z.Y. Zhong*, and Z. Liu*,Gold Nanorod-Cored Biodegradable Micelles as a Robust and Remotely Controllable Doxorubicin Release System for Potent Inhibition of Drug-Sensitive and -Resistant Cancer Cells,Biomacromolecules2013, 14, 2411-2419.

  233. L.L. Wu, Y. Zou, C. Deng*,R. Cheng, F.H. Meng, andZ.Y. Zhong*,Intracellular Release of Doxorubicin from Core-Crosslinked Polypeptide Micelles Triggered by Both pH and Reduction Conditions, Biomaterials2013,34, 5262-5272.

  234. W. Chen,M. Zheng, F.H. Meng, R. Cheng, C. Deng, J. Feijen, andZ.Y. Zhong*,In Situ Forming Reduction-Sensitive Degradable Nanogels for Facile Loading and Triggered Intracellular Release of Proteins,Biomacromolecules2013,14, 1214-1222.

  235. H.L. Sun, F.H. Meng*,R. Cheng, C. Deng, andZ.Y. Zhong*,Reduction-Sensitive Degradable Micellar Nanoparticlesas Smartand Intuitive Delivery Systemsfor Cancer Chemotherapy,Expert Opin. Drug Deliv.2013, 10, 1109-1122.

  236. R. Cheng, F.H. Meng, C. Deng,H.A. Klok, andZ.Y. Zhong*,Dual and Multi-Stimuli Responsive Polymeric Nanoparticlesfor Programmed Site-Specific Drug Delivery,Biomaterials2013, 34,3647-3657.

  237. J. Feijen, andZ.Y. Zhong*,The Second Symposium on Innovative Polymers for Controlled Delivery, September 11-14, 2012, Suzhou, China,J. Control. Release2013, 169, 163-164.

  238. W. Chen,P. Zhong, F.H. Meng*, R. Cheng, C. Deng, J. Feijen, andZ.Y. Zhong*,Redox and pH-ResponsiveDegradableMicelles forDuallyActivatedIntracellularAnticancerDrugRelease,J. Control. Release2013, 169, 171-179.

  239. J. Feijen, W.E. Hennink​‌,andZ.Y. Zhong*,Conference Scene: From Innovative PolymersTo Advanced Nanomedicine: Key Challenges, Recent Progressand Future Perspectives,Nanomedicine2013, 8, 177-180.

  240. W. Chen, Y. Zou, J.N. Jia, F.H. Meng, R. Cheng, C. Deng, J. Feijen, andZ.Y. Zhong*,Functional Poly(ε-caprolactone)s via Copolymerization ofε Caprolactone and Pyridyl Disulfide-Containing Cyclic Carbonate: Controlled Synthesis and Facile Access to Reduction-Sensitive Biodegradable Graft Copolymer Micelles,Macromolecules2013,46, 699-707.

  241. F.H. Meng, R. Cheng, C. Deng, andZ.Y. Zhong*, Intracellular Drug Release Nanosystems,Materials Today2012, 15, 436-442 (invited review)

  242. Y.L. Wu, W. Chen,F.H. Meng, Z.J. Wang,R. Cheng, C. Deng, H.Y. Liu, andZ.Y. Zhong*,Core-Crosslinked pH-Sensitive Degradable Micelles: A Promising Approachto Resolvethe Extracellular Stability Versus Intracellular Drug Release Dilemma,J. Control. Release2012,164, 338-345.

  243. C. Deng,Y.J. Jiang,R. Cheng, F.H. Meng, andZ.Y. Zhong*, Biodegradable Polymeric Micelles for Targeted and Controlled Anticancer Drug Delivery: Promises, Progress and Prospects,Nano Today2012,7, 467-480 (invited review)

  244. R.R. Wei, L. Cheng, M. Zheng,R. Cheng, F.H. Meng, C. Deng, andZ.Y. Zhong*, Reduction-Responsive Disassemblable Core-Cross-Linked Micelles Based on Poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide)–Lipoic Acid Conjugates for Triggered Intracellular Anticancer Drug Release,Biomacromolecules2012,13, 2429-2438.

  245. S.K. Li,F.H. Meng,Z.J. Wang, Y.N. Zhong, M. Zheng,H.Y. Liu, andZ.Y. Zhong*, Biodegradable Polymersomeswith An Ionizable Membrane: Facile Preparation, Superior Protein Loading, And EndosomalpH-Responsive Protein Release,Eur.J. Pharm. Biopharm.2012, 82, 103-111 (invited article)

  246. Y.F.Du, W. Chen,M. Zheng,F.H. Meng, andZ.Y. Zhong*,pH-Sensitive Degradable Chimaeric Polymersomesforthe Intracellular Releaseof Doxorubicin Hydrochloride,Biomaterials2012,33,7291-7299.

  247. R. Cheng, X.Y. Wang, W. Chen, F.H. Meng, C. Deng, H.Y. Liu, andZ.Y. Zhong*, Biodegradable Poly(ε-caprolactone)-g-Poly(2-hydroxyethyl methacrylate) Graft Copolymer Micelles as Superior Nano-Carriers for “Smart” Doxorubicin Release,J. Mater. Chem.2012,22, 11730-11738.

  248. M. Zheng,Z.H.Zhong,L.Zhou, F.H. Meng,R. Peng, andZ.Y. Zhong*,Poly(ethylene oxide) Grafted with Short Polyethylenimine Gives DNA Polyplexes with Superior Colloidal Stability, Low Cytotoxicity and Potent In Vitro Gene Transfection Under Serum Conditions,Biomacromolecules2012,13, 881–888.

  249. W. Wang, H.L. Sun,F.H. Meng, S.B. Ma, H.Y. Liu,andZ.Y. Zhong*,Precise Control of Intracellular Drug Release and Anti-Tumor Activity of Biodegradable Micellar Drugs Via Reduction-Sensitive Shell-Shedding,Soft Matter2012, 8, 3949-3956.

  250. C.H. Zhu, M. Zheng, F.H. Meng, F.M. Mickler, N. Ruthardt, X.L. Zhu, andZ.Y. Zhong*,Reversibly Shielded DNA Polyplexes Based on Bioreducible PDMAEMA-SS-PEG-SS-PDMAEMA Triblock Copolymers Mediate Markedly Enhanced Nonviral Gene Transfection,Biomacromolecules2012, 13, 769–778.

  251. J.C. Zhang,L.L. Wu,F.H. Meng, Z.J. Wang,C.Deng,H.Y. Liu, andZ.Y. Zhong*,pH and Reduction Dual-Bioresponsive Polymersomes for Efficient Intracellular Protein Delivery,Langmuir2012, 28,2056–2065. (invited article)

  252. M. Zheng, C.M. Yang, F.H. Meng, R. Peng, andZ.Y. Zhong*,pH-Sensitive Degradable Hydrophobe Modified 1.8 kDa Branched Polyethylenimine,as “Artificial Viruses” for Safe and Efficient Intracellular Gene Transfection,Macromol. Res.2012,20, 327-334(InvitedArticle)

  253. F.X. Zhan, W. Chen, Z.J. Wang, W.T. Lu, R. Cheng,C. Deng,F.H. Meng,H.Y. Liu andZ.Y. Zhong*,Acid-Activatable Prodrug Nanogels for Efficient Intracellular Doxorubicin Release,Biomacromolecules2011,12, 3612–3620.

  254. R. Cheng, F.H. Meng, S.B. Ma, H.F. Xu, H.Y. Liu, X.B. Jing,andZ.Y. Zhong*, Reduction and Temperature Dual-Responsive Crosslinked Polymersomes for Targeted Intracellular Protein Delivery,J. Mater. Chem.2011,21, 19013-19020.

  255. M. Zheng,Y.N. Zhong,F.H. Meng, R. Peng, andZ.Y. Zhong*,Lipoic Acid Modified Low Molecular Weight Polyethylenimine Mediates Nontoxic and Highly Potent In Vitro Gene Transfection,Mol. Pharmaceutics, 2011,8, 2434-2443.

  256. Z.Z. Liu,M. Zheng, F.H. Meng, andZ.Y. Zhong*,Non-Viral Gene Transfection In Vitro Using EndosomalpH-Sensitive Reversibly Hydrophobilized Polyethylenimine,Biomaterials2011,32,9109-9119.

  257. R. Wang, W. Chen, F.H. Meng, R. Cheng,C. Deng, J. Feijen,andZ.Y. Zhong*, Unprecedented Access to Functional Biodegradable Polymers and Coatings,Macromolecules2011,44, 6009–6016.

  258. Y.H. Cong, H. Liu, D.L. Wang, B.J. Zhao, T.Z. Yan, L.B. Li , W. Chen,Z.Y. Zhong , M.-C. Lin, H.-L. Chen,andC.L. Yang,Stretch-Induced Crystallization through Single Molecular Force Generating Mechanism,Macromolecules2011,44,5878-5882.

  259. J. Chen, W. Chen,C. Deng,F.H. Meng, andZ.Y. Zhong*, Controlled Surface-Initiated Ring-Opening Polymerization of L-Lactide from Risedronate-Anchored Hydroxyapatite Nanocrystals: Novel Synthesis of Biodegradable Hydroxyapatite/Poly(L-lactide) Nanocomposites,J. Polym. Sci. Part  A: Polym. Chem.2011, 49,4379-4386.

  260. R.Yang, F.H. Meng,S.B. Ma,F.S. Huang,H.Y. Liu, andZ.Y.Zhong*,Galactose-Decorated Crosslinked Biodegradable Poly(Ethylene Glycol)-b-Poly(ε-Caprolactone) Block Copolymer Micelles for Enhanced Hepatoma-Targeting Delivery of Paclitaxel,Biomacromolecules2011,12, 3047–3055.

  261. Y.X. Yu,C. Deng, F.H. Meng,Q. Shi,J. Feijen,andZ.Y. Zhong*, Novel Injectable Biodegradable Glycol Chitosan-Based Hydrogels Crosslinkedby Michael-Type Addition Reactionwith Oligo(acryloylcarbonate)-b-Poly(ethyleneglycol)-b-Oligo(acryloylcarbonate) Copolymers,J. Biomed. Mater. Res. Part A2011, 99A,316-326.

  262. S.B. Luo,R. Cheng,F.H. Meng, T.G. Park, andZ.Y. Zhong*,Water Soluble Poly(histamine acrylamide) with Superior Buffer CapacityMediates Efficient and Nontoxic In Vitro Gene Transfection,J. Polym. Sci. Part  A: Polym. Chem.2011,49,3366–3373.

  263. F.H. Meng,andZ.Y. Zhong*, Polymersomes Spanning from Nano to Micro Scales: Advanced Vehicles for Controlled Drug Delivery and Robust Vesicles for Virus and Cell-Mimicking,J. Phys. Chem. Letters2011, 2, 1533-1539.(Invited Perspective)

  264. H.L. Sun, F.H. Meng, A.A. Dias, M. Hendriks, J. Feijen, andZ.Y. Zhong*,-Amino Acid Containing Degradable Polymers as Functional Biomaterials: Rational Design, Synthetic Pathway and Biomedical Applications,Biomacromolecules2011,12, 1937-1955.

  265. J. Xiong, F.H. Meng,C. Wang, R. Cheng, Z. Liu, andZ.Y. Zhong*, Folate-Conjugated Crosslinked Biodegradable Micelles for Receptor-Mediated Delivery of Paclitaxel,J. Mater. Chem.2011, 21, 5786-5794.

  266. L. Zhou, R. Cheng, H.Q. Tao, S.B. Ma, W.W. Guo, F.H. Meng,H.Y. Liu, Z. Liu, andZ.Y.Zhong*,Endosomal pH-Activatable Poly(ethylene oxide)-graft-Doxorubicin Prodrugs: Synthesis, Drug Release, and Biodistribution in Tumor-Bearing Mice,Biomacromolecules2011,12, 1460–1467.

  267. Y.H. Wang, M. Zheng, F.H. Meng, J. Zhang, R. Peng, andZ.Y. Zhong*,Branched Polyethylenimine Derivatives with Reductively Cleavable Periphery for Safe and Efficient In Vitro Gene Transfer,Biomacromolecules2011, 12, 1032-1040.

  268. R. Cheng, F. Feng, F.H. Meng, C. Deng, J. Feijen,Z.Y. Zhong*,Glutathione-Responsive Nano-Vehicles as a Promising Platform for Targeted Intracellular Drugand GeneDelivery,J. Control. Release2011,152, 2-12.

  269. Z.Y. Zhong*,andJ. Feijen, The First Symposium on Innovative Polymers for Controlled Delivery, September 14-17, 2010, Suzhou, China,J. Control. Release2011, 152, 1-1.

  270. G.J. Liu, S.B. Ma, S.K. Li, R. Cheng, F.H. Meng,*, H.Y. Liu,Z.Y. Zhong*,The highly efficient delivery of exogenous proteins into cells mediatedby biodegradable chimaeric polymersomes,Biomaterials2010, 31, 7575-7585.

  271. R. Jin,L.S.MoreiraTeixeira, P.J. Dijkstra,Z.Y.Zhong, C.A. van Blitterswijk,M.Karperien, J. Feijen,Enzymatically crosslinked dextran-tyramine hydrogels as injectable scaffolds for cartilage tissue engineering,Tissue EngineeringPart A.2010,16,2429-2440.

  272. C.H. Zhu, S.Y. Jung,G.Y.Si,R. Cheng,F.H. Meng*, X.L. Zhu, T.G. Park, andZ.Y. Zhong*,Cationic methacrylate copolymers containing primary and tertiary amino side groups:controlled synthesis via RAFT polymerization, DNA condensation, and in vitro gene transfection,J. Polym. Sci. Part  A: Polym. Chem.2010,48, 2869–2877.

  273. H.L. Sun, F.H. Meng*, B.N. Guo,X.Q. Li, R. Cheng, H.Y. Liu, andZ.Y. Zhong*,Shell-sheddable micelles based on dextran-ss-poly(-caprolactone) diblock copolymer for efficient intracellular release of doxorubicin,Biomacromolecules2010,11, 848–854.

  274. R. Namgung, J.H. Brumbach, J.H. Jeong, J.W. Yockman, S.W. Kim, C. Lin,Z.Y. Zhong, J. Feijen, J.F.J. Engbersen, and W.J.Kim*, Dual bio-responsive gene delivery via reducible poly(amido amine) and survivin-inducible plasmid DNA,Biotechnol. Lett.2010, 32,755-764.

  275. C.H. Zhu, S.Y. Jung, S.B. Luo, F.H. Meng, X.L. Zhu, T.G. Park, andZ.Y. Zhong*,Co-delivery of siRNA and Paclitaxel into Cancer Cells by Biodegradable Cationic Micelles Based on PDMAEMA-PCL-PDMAEMA Triblock Copolymers,Biomaterials2010,31, 2408–2416.

  276. W. Chen, F.H. Meng*, R. Cheng, and Z.Y. Zhong*,pH-Sensitive Degradable Polymersomes for Triggered Release of Anticancer Drugs: a Comparative Study with Micelles,J. Control. Release2010, 142, 40-46.

  277. W. Chen, H.C. Yang, R. Wang, R. Cheng, F.H. Meng*, W.X. Wei, andZ.Y. Zhong*, Versatile Synthesis of Functional Biodegradable Polymers by CombiningRing-Opening Polymerization and Postpolymerization Modification viaMichael-Type Addition Reaction,Macromolecules2010, 43, 201–207.

  278. J.M. Jukes, L.J. van der Aa, C. Hiemstra, T. van Veen, P.J. Dijkstra,Z.Y.Zhong, J. Feijen, C.A. van Blitterswijk, J. de Boer,A newly developed chemically crosslinked Dex-PEGhydrogel for cartilage tissue engineering,Tissue EngineeringPart A.2010, 16: 565-573.

  279. Y.L. Li, L. Zhu, Z.Z. Liu, R. Cheng, F.H. Meng*, J.H. Cui, S.J. Ji, and Z.Y. Zhong*, Reversibly Stabilized Multifunctional Dextran Nanoparticles Efficiently Deliver Doxorubicin into the Nuclei of Cancer Cells,Angew. Chem.Int. Ed.2009, 48, 9914-9918.

  280. Y.M. Xu, F.H. Meng*, R. Cheng,Z.Y. Zhong*,Reduction-Sensitive Reversibly Crosslinked Biodegradable Micelles for Triggered Release of Doxorubicin,Macromol. Biosci.2009, 9, 1254-1261.

  281. H.Z. Du, A.H. Velders, P.J. Dijkstra,Z.Y. Zhong, X.S. Chen, J. Feijen, Chiral Salan Aluminum Ethyl Complexes and Their Application in Lactide Polymerization,Chem.-Eur. J.2009, 15: 9836-9845.

  282. H.L. Sun, B.N. Guo, R. Cheng, F.H. Meng *, H.Y. Liu,Z.Y. Zhong*,Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin, Biomaterials2009, 30: 6358-6366.

  283. W.Chen, F.H. Meng, F. Li, S.-J. Ji,Z.Y. Zhong*,pH-Responsive Biodegradable Micelles Based on Acid-Labile Polycarbonate Hydrophobe: Synthesis and Triggered Drug Release,Biomacromolecules2009, 10: 1727-1735.

  284. H.F. Xu, F.H. Meng*, Z.Y. Zhong*, Reversibly crosslinked temperature-responsive nano-sized polymersomes: synthesis and triggered drug release,J. Mater. Chem.2009, 19: 4183-4190.

  285. F.H. Meng, W.E.Hennink, Z.Y. Zhong*, Reduction-Sensitive Polymers and Bioconjugates for Biomedical Applications,Biomaterials2009, 30:2180-2198.

  286. R. Jin, L.S. Moreira Teixeira, P.J. Dijkstra, M. Karperien,Z.Y. Zhong, J. Feijen,Injectable Chitosan-based Hydrogels for Cartilage Tissue Engineering,Biomaterials2009, 30:2544-2551

  287. H.Z. Du, A.H. Velders, P.J. Dijkstra,Z.Y. Zhong,X.S. Chen, J. Feijen,Polymerization oflactideusingachiralbis(pyrrolidene)schiffbasealuminumcomplexes,Macromolecules2009, 42: 1058–1066.

  288. F.H. Meng, Z.Y. Zhong*, J. Feijen, Stimuli-responsive polymersomes for programmed drug delivery.Biomacromolecules2009,10: 197-209.

  289. C. Lin, C.-J. Blaauboer, M.Mateos Timoneda, M.C. Lok, M. van Steenbergen, W.E. Hennink,Z.Y. Zhong, J. Feijen, and J.F.J. Engbersen,Bioreduciblepoly(amido amine)s with oligoamine side chains: Synthesis, characterization, and structural effects on gene delivery,J. Control. Release,2008, 126: 166-174.

  290. C. Lin,Z.Y. Zhong, M.C. Lok, Holger K. de Wolf, W.E. Hennink, J. Feijen, J.F.J. Engbersen, Bioreducible poly(amido amine)s for gene delivery to ovarian cancer cells,J. Control. Release,2008, 132:e9-e10.

  291. R. Jin, L.S. Moreira Teixeira, P.J. Dijkstra, M. Karperien,Z. Zhong, J. Feijen,Fast in-situ formation of dextran-tyramine hydrogels for in vitro chondrocyte culturing,J. Control. Release,2008, 132:e24-e26.

  292. C.Hiemstra, W. Zhou,Z.Y. Zhong*, M. Wouters, and J Feijen*,Rapidly in situ forming biodegradable robust hydrogels by combining stereocomplexation and photopolymerization,J. Am. Chem. Soc.2007, 129: 9918-9926.

  293. M. Roerdink, T.S. van Zanten, M.A. Hempenius,Z.Y. Zhong, J. Feijen, and G.J. Vancso, Poly(ferrocenylsilane-block-lactide) Block copolymers,Macromol. Rapid Commun. 2007, 28: 2125-2130.

  294. C. Lin,Z.Y. Zhong*, M.C. Lok, X.L. Jiang, W.E. Hennink, J. Feijen, and J.F.J. Engbersen*, Random and block copolymers of bioreducible poly(amido amine)s with high-and low-basicity amino groups: study of DNA condensation and buffer capacity on gene transfection,J. Control. Release,2007, 123: 67-75.

  295. C. Hiemstra,Z.Y. Zhong*, M. J. van Steenbergen, W.E. Hennink, and J. Feijen*, Release of model proteins and basic fibroblast growth factor from in situ forming degradable dextran hydrogels,J. Control. Release2007, 122: 71-78.

  296. C. Hiemstra,Z.Y. Zhong*, S.R. van Tomme, M. J. van Steenbergen, J.J.L. Jacobs, W. den Otter, W.E. Hennink, and Jan Feijen*，In vitro and in vivo protein delivery from in situ forming poly(ethylene glycol)-poly(lactide) hydrogels,J. Control. Release2007, 119: 320-327.

  297. C. Hiemstra, L.J. van der Aa,Z.Y. Zhong*, and J. Feijen*, Rapidly in situ forming degradable hydrogels from dextran thiols through Michael addition,Biomacromolecules 2007, 8: 1548-1556.

  298. F. Rusmini,Z.Y. Zhong*, and J. Feijen*, Protein immobilization strategies for protein biochips,Biomacromolecules2007, 8: 1775-1789.

  299. R. Jin, C. Hiemstra,Z.Y. Zhong*, and J. Feijen*, Enzyme-mediated fast in-situ formation of hydrogels from dextran-tyramine conjugates,Biomaterials2007, 28: 2791-2800.

  300. C. Hiemstra, L.J. van der Aa,Z.Y. Zhong*, P.J. Dijkstra, and J. Feijen*, Novel in situ forming, degradable dextran hydrogels by Michael addition chemistry: synthesis, rheology and degradation,Macromolecules2007, 40: 1165-1173.

  301. L.V. Christensen, C.W. Chang, J.W. Yockman, R. Conners, H. Jackson, D.A. Bull,Z.Y. Zhong, J. Feijen, and S.W. Kim, Reducible poly(amido ethylenediamine) for hypoxia-inducible VEGF delivery,J. Control. Release2007, 118: 254-261.

  302. J.H. Jeong, L.V. Christensen, J.W. Yockman,Z.Y. Zhong, J.F.J. Engbersen, W.J. Kim, J. Feijen, S.W. Kim, Reducible poly(amido ethylenimine) directed to enhance RNA interference,Biomaterials2007,28: 1912-1917.

  303. C. Lin,Z.Y. Zhong*, M.C. Lok, X.L. Jiang, W.E. Hennink, J. Feijen, and J.F.J. Engbersen*, Novel bioreducible poly(amido amine)s for highly efficient gene delivery,Bioconjugate Chem.2007，18: 138-145.

  304. L.B. Li, F.H. Meng,Z.Y. Zhong, D. Byelov, W.H. de Jeu, and J. Feijen, Morphology of a highly asymmetric double crystallizable poly(-caprolactone-b-ethylene oxide) block copolymer,J. Chem. Phys.,2007,126:  Art. No. 024904.

  305. M.R. ten Breteler,Z.Y. Zhong, P.J. Dijkstra, and J. Feijen, Ring-opening polymerization of substituted-caprolactones using a chiral (salen) AlOiPr-Complex,J. Polym. Sci. Part  A, Polym. Chem.2007,45: 429-436.

  306. C. Lin,Z.Y. Zhong*, M.C. Lok, X.L. Jiang, W.E. Hennink, J. Feijen, and J.F.J. Engbersen*, Linear poly(amido amine)s with secondary and tertiary amino groups and variable amounts of disulfide linkages: synthesis and in vitro gene transfer properties,J. Control. Release,2006, 116: 130-137.

  307. C. Hiemstra,Z.Y. Zhong, X. Jiang, W.E. Hennink, P.J. Dijkstra, and J. Feijen, PEG-PLLA and PEG-PDLA multiblock copolymers: synthesis and in situ hydrogel formation by stereocomplexation,J. Control. Release, 2006, 116: e17-e19.

  308. C. Hiemstra,Z.Y. Zhong, S.R. van Tomme, W.E. Hennink, P.J. Dijkstra, and J. Feijen, Protein release from injectable stereocomplexed hydrogels based on PEG-PDLA and PEG-PLLA star block copolymers,J. Control. Release,2006, 116: e19-e21.

  309. C. Lin, T.M. Lammens,Z.Y. Zhong, H. Gu, M.C. Lok, X. Jiang, W.E. Hennink, J. Feijen, and J.F.J. Engbersen, Disulfide-containing poly(β-amino ester)s for gene delivery,J. Control. Release,2006, 116: e79-e81.

  310. Z.Y. Zhong*, C. Lin, Y. Ma, M.A. Hempenius, M.C. Lok, M.M. Fretz, J.F.J. Engbersen, G.J. Vancso, W.E. Hennink, and J. Feijen, Water-soluble cationic poly(ferrocenylsilane): an efficient DNA condensation and transfection agent,J. Control. Release,2006, 116: e81-e83.

  311. C. Hiemstra,Z.Y. Zhong*, L.B. Li, P.J. Dijkstra, and J. Feijen*, In situ formation of biodegradable hydrogels by stereocomplexation of PEG-(PLLA)8 and PEG-(PDLA)8 star block copolymers,Biomacromolecules2006, 7: 2790-2795.

  312. L.V. Christensen, C.W. Chang, W.J. Kim, S.W. Kim*,Z.Y. Zhong*, C. Lin, J.F.J. Engbersen*, and J. Feijen, Reducible poly(amido ethylenimine)s designed for triggered intracellular gene delivery,Bioconjugate Chem.,2006, 17: 1233-1240.

  313. M. Leemhuis, C.F. van Nostrum, J.A.W. Kruijtzer,Z.Y. Zhong, M.R. ten Breteler, P.J. Dijkstra, J. Feijen, and W.E. Hennink,Functionalized poly(-hydroxy acid)s via ring-opening polymerization: toward hydrophilic polyesters with pendant hydroxyl groups,Macromolecules,2006, 39: 3500-3508.

  314. G. Engbers, A. Poot, D. Grijpma,Z.Y. Zhong, and P. Dijkstra, Professor Jan Feijen-30 years research in biomedical technology,J. Control. Release2005,109: 2-4.

  315. Z.Y. Zhong, J. Feijen, M.C. Lok, W.E. Hennink, L. Christensen, J.W. Yockman, Y.-H. Kim, and S.W. Kim, Low molecular weight linear polyethylenimine-b-poly(ethylene glycol)-b-polyethylenimine triblock copolymers: synthesis, characterization and in vitro gene transfer properties,Biomacromolecules,2005, 6: 3440-3448.

  316. Z.Y. Zhong, Y. Song, J.F.J. Engbersen, M.C. Lok, W.E. Hennink, and J. Feijen, A versatile family of degradable non-viral gene carriers based on hyperbranched poly(ester amine)s.J. Control. Release2005, 109: 317-329.

  317. C. Hiemstra,Z.Y. Zhong, P. Dijkstra, and J. Feijen, Stereocomplex mediated gelation of PEG-(PLA)(2) and PEG-(PLA)(8) block copolymers.Macromol. Symp.,2005, 224: 119-131.

  318. Z. Zhong, M.C. Lok, P.J. Dijkstra, W.E. Hennink, and J. Feijen, Structurally well-defined copolymers of poly(ethylene glycol) and low molecular weight linear polyethylenimine as vectors for gene delivery.J. Control. Release,2005, 101(1-3): 406-408.

  319. C. Hiemstra,Z. Zhong, P.J. Dijkstra, and J. Feijen, PEG-PLA hydrogels by stereocomplexation for tissue engineering of cartilage.J. Control. Release,2005, 101(1-3): 332-334.

  320. G. Becker, M. Niemeyer, O. Mundt, W. Schwarz, M. Westerhausen, M.W. Ossberger, P. Mayer, H. Noth,Z.Y. Zhong, P.J. Dijkstra, and J. Feijen, Crystal structures and spectroscopic properties of 2 lambda(3)-phospha-1,3-dionates and 1,3-dionates of calcium - Comparative studies on the 1,3-diphenyl and 1,3-Di(tert-butyl) derivatives.Z. Anorg. Allg. Chem.,2004, 630(15): 2605-2621.

  321. Z.Y. Zhong, P.J. Dijkstra, and J. Feijen, Controlled synthesis of biodegradable lactide polymers and copolymers using novel in situ generated or single-site stereoselective polymerization initiators.J. Biomater. Sci.-Polym. Ed.,2004, 15(7): 929-946.

  322. L.B. Li,Z.Y. Zhong, W.H. de Jeu, P.J. Dijkstra, and J. Feijen, Crystal structure and morphology of poly(L-lactide-b-D-lactide) diblock copolymers.Macromolecules,2004, 37(23): 8641-8646.

  323. M. Westerhausen, S. Schneiderbauer, A.N. Kneifel, Y. Soltl, P. Mayer, H. Noth,Z.Y. Zhong, P.J. Dijkstra, and J. Feijen, Organocalcium compounds with catalytic activity for the ring-opening polymerization of lactones.Eur. J. Inorg. Chem.,2003, (18): 3432-3439.

  324. Z.Y. Zhong, P.J. Dijkstra, and J. Feijen, Determination of the Stereoselectivity Factor for an Asymmetric Enantiomer-Differentiating Polymerization: a Revisit.Macromolecules,2003, 36(21): 8198-8200.

  325. Z.Y. Zhong, S. Schneiderbauer, P.J. Dijkstra, W. M., and J. Feijen, Single-site calcium initiators for the controlled ring-opening polymerization of lactides and lactones.Polym. Bull.,2003, 51: 175-182.

  326. Z.Y. Zhong, P.J. Dijkstra, and J. Feijen, controlled and stereoselective polymerization of lactide: kinetics, selectivity, and microstructures.J. Am. Chem. Soc.,2003, 125(37): 11291-11298.

  327. A.P. Pego,Z.Y. Zhong, P.J. Dijkstra, D.W. Grijpma, and J. Feijen, Influence of catalyst and polymerization conditions on the properties of 1,3-trimethylene carbonate and epsilon- caprolactone copolymers.Macromol. Chem. Phys.,2003, 204(5-6): 747-754.

  328. Z.Y. Zhong, P.J. Dijkstra, and J. Feijen, [(salen)Al]-mediated, controlled and stereoselective ring-opening polymerization of lactide in solution and without solvent: Synthesis of highly isotactic polylactide stereocopolymers from racemic D,L-lactide.Angew. Chem.Int. Edit.,2002, 41(23): 4510-4513.

  329. Z.Y. Zhong, P.J. Dijkstra, J. Feijen, Y.M. Kwon, Y.H. Bae, and S.W. Kim, Synthesis and aqueous phase behavior of thermoresponsive biodegradable poly(D,L-3-methylglycolide)-block-poly(ethylene glycol)-block-poly(D,L-3-methylglycolide) triblock copolymers.Macromol. Chem. Phys.,2002, 203(12): 1797-1803.

  330. Z.Y. Zhong, S. Schneiderbauer, P.J. Dijkstra, M. Westerhausen, and J. Feijen, Fast and living ring-opening polymerization of L-lactide initiated with in-situ-generated calcium alkoxides.J. Polym. Environ.,2001, 9(1): 31-38.

  331. Z.Y. Zhong, M.J.K. Ankone, P.J. Dijkstra, C. Birg, M. Westerhausen, and J. Feijen, Calcium methoxide initiated ring-opening polymerization of epsilon-caprolactone and L-lactide.Polym. Bull.,2001, 46(1): 51-57.

  332. Z.Y. Zhong, P.J. Dijkstra, C. Birg, M. Westerhausen, and J. Feijen, A novel and versatile calcium-based initiator system for the ring-opening polymerization of cyclic esters.Macromolecules,2001, 34(12): 3863-3868.

  333. Z.Y. Zhong, P.J. Dijkstra, and J. Feijen, Controlled ring-opening polymerization of omega- pentadecalactone with yttrium isopropoxide as an initiator.Macromol. Chem. Phys.,2000, 201(12): 1329-1333.

  334. Z.Y. Zhong, D.H. Yu, F.H. Meng, Z.H. Gan, and X.B. Jing, Controlled synthesis of L-lactide-b-epsilon-caprolactone block copolymers using a rare earth complex as catalyst.Polym. J.,1999, 31(8): 633-636.

  335. Z.H. Gan, D.H. Yu,Z.Y. Zhong, Q.Z. Liang, and X.B. Jing, Enzymatic degradation of poly(epsilon-caprolactone)/poly(DL- lactide) blends in phosphate buffer solution.Polymer,1999, 40(10): 2859-2862.

  336. J. Zhang, Z.H. Gan,Z.Y. Zhong, and X.B. Jing, A novel rare earth coordination catalyst for polymerization of biodegradable aliphatic lactones and lactides.Polym. Int.,1998, 45(1): 60-66.