邓超
时间:2019-12-26

邓超,博士,教授,博导1975年11月出生于四川省三台县。2006年7月在中国科学院长春应用化学研究所高分子化学与物理专业获博士学位(导师:景遐斌、陈学思研究员)。2006年8月—2010年5月在加拿大渥太华大学眼睛所、心脏所和细胞分子生物医学系从事博士后研究(合作导师:May Griffith, Erik Suuronen)。2010年6月起受聘为苏州大学副教授,2014年晋升为教授。在国际主流期刊如Prog. Polym. Sci., Biomaterials, Nano Today, J. Controlled Release, Chem. Mater., Macromolecules, Biomacromolecules, Tissue Eng., Acta Biomater. 等上发表论文100多篇,被引用7600多次,H-因子45。多篇论文被MaterialsViewChina,中国聚合物网和高分子科技等作为研究亮点进行专题报道。申请中国发明专利12项和国际发明专利2项,授权中国发明专利7项。担任了五届“新型高分子材料与控制释放国际会议”(SIPCD 2010, 2012, 2014, 2016, 2018)”的秘书长,并多次在国际会议上作报告。现主持两项国家自然科学基金面上项目。主要研究方向为生物医用高分子的设计合成、聚多肽纳米药物载体、可注射性微凝胶和水凝胶等。曾获加拿大心脏及中风基金委研究奖学金(2010-2012年),加拿大渥太华心脏研究所分子功能和图像研究奖学金(2008-2010年),苏州市高等院校、科研院所紧缺高层次人才资助(2010-2011年),苏州市自然科学优秀学术论文二等奖(2012-2013年),2018年度药理学和毒理学领域全球高被引科学家(科睿唯安,Clarivate Analytics)。


代表性论著

2019

1.    X.L. Gu, Z.H. Zhu, Q.Y. Fan, Y.H. Wei, G.L. Wang, F.H. Meng, Z.Y. Zhong*, and C. Deng*, Nanoagents based on poly(ethylene glycol)-b-poly(L-thyroxine) block copolypeptide for enhanced dual-modality imaging and targeted tumor radiotherapy, Small2019, 1902577.

2.    X.L. Gu, Y.H. Wei, Q.Y. Fan, H.L. Sun, R. Cheng, Z.Y. Zhong*, and C. Deng*, cRGD-decorated biodegradable polytyrosine nanoparticles for robust encapsulation and targeted delivery of doxorubicin to colorectal cancer in vivo, J. Control. Release2019, 301, 110-118.

3.    K. Huang, Y.H. He, Z.H. Zhu, J.K. Guo, G.L. Guang, C. Deng*, and Z.Y. Zhong*, Small, traceable, endosome-disrupting, and bioresponsive click nanogels fabricated via microfluidics for CD-targeted cytopla**ic delivery of therapeutic proteins, ACS Appl. Mater. Interfaces2019, 11, 22171-22180.

4.    M. Qiu, J. Ouyang, Y.H. Wei, J. Zhang, Q. Lan, C. Deng*, and Z.Y. Zhong*, Selective cell penetrating peptide-functionalized envelope-type chimeric lipopepsomes boost systemic RNAi therapy for lung tumors, Adv. Healthcare. Mater.2019, 8, 1900500.

5.    H.M. Fang, X.F. Zhao, X.L. Gu, H.L. Sun, R. Cheng, Z.Y. Zhong*, and C. Deng*, CD44-targeted multifunctional nanomedicines based on a single-component hyaluronic acid conjugate with all-natural precursors: construction and treatment of metastatic breast tumors in vivo, Biomacromolecules2019, DOI: 10.1021/acs.biomac.9b01012.

6.    H.Z. Qin, Y. Jiang, J. Zhang, C. Deng*, and Z.Y. Zhong*, Oncoprotein inhibitor rigosertib loaded in apoe-targeted **art polymersomes reveals high safety and potency against human glioblastoma in mice, Mol. Pharmaceutics2019, 16, 3711-3719.

7.    J. Chen, H. He, C. Deng*, L.C. Yin, and Z.Y. Zhong*, Saporin-loaded CD44 and EGFR dual-targeted nanogels for potent inhibition of metastatic breast cancer in vivo, Int.J. Pharm. 2019, 560, 57-64.

8.    D. Kuraitis, K. Hosoyama, N. J. R. Blackburn, C. Deng, Z. Zhong*, E. J. Suuronen*, Functionalization of soft materials for cardiac repair and regeneration. Crit. Rev. Biotechnol.2019, 39, 451-468.

9.    N. Rades, K. Achazi, M. Qiu, C. Deng, R. Haag, Z.Y. Zhong*, and K. Licha*, Reductively cleavable polymer-drug conjugates based on dendritic polyglycerol sulfate and monomethyl auristatin E as anticancer drugs, J. Control. Release2019, 300, 13-21.

2018

10.  M. Qiu, H.L. Sun, F.H. Meng, R. Cheng, J. Zhang, C. Deng*, and Z.Y. Zhong*, Lipopepsomes: A novel and robust family of nano-vesicles capable of highly efficient encapsulation and tumor-targeted delivery of doxorubicin hydrochloride in vivo, J. Control. Release2018, 272, 107-113.

11.  M. Qiu, X.X. Wang, H.L. Sun, J. Zhang, C. Deng*, and Z.Y. Zhong*, Cyclic RGD-peptide-functionalized polylipopeptide micelles for enhanced loading and targeted delivery of monomethyl auristatin E, Mol. Pharmaceutics2018, 15, 4854-4861.

12.  J. Chen, K. Huang, Q.J. Chen, C. Deng*, J. Zhang, and Z.Y. Zhong*, Tailor-Making Fluorescent Hyaluronic Acid Microgels via Combining Microfluidics and Photoclick Chemistry for Sustained and Localized Delivery of Herceptin in Tumor, ACS Appl. Mater. Interfaces2018, 10, 3929-3937.

13.  M. Qiu, Z.Q. Zhang, Y.H. Wei, H.L. Sun, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Small-sized and robust chimaeric lipopepsomes: A simple and functional platform with high protein loading for targeted intracellular delivery of protein toxin in vivo, Chem. Mater. 2018, 30, 6831-6838.

14.  S. Xue, X.L. Gu, J. Zhang, H.L. Sun, C. Deng*, and Z.Y. Zhong*, Construction of **all-sized, robust, and reduction-responsive polypeptide micelles for high loading and targeted delivery of chemotherapeutics, Biomacromolecules 2018, 19, 3586-3593.

15.  X.L. Gu, M. Qiu, H.L. Sun, J. Zhang, L. Cheng, C. Deng*, and Z.Y. Zhong*,Polytyrosine nanoparticles enable ultra-high loading of doxorubicin and rapidly enzyme-responsive drug release, Biomater.Sci.2018, 6, 1526-1534.

16.  T. Chen, M. Qiu, J. Zhang, H.L. Sun, C. Deng*, and Z.Y. Zhong*, Integrated Multifunctional Micelles Co-Self-Assembled from Polypeptides Conjugated with Natural Ferulic Acid and Lipoic Acid for Efficient and Bioresponsive Doxorubicin Delivery, ChemPhysChem2018, 19, 2070-2077.

17.  Y.Q. Zhu, Y. Jiang, F.H. Meng, C. Deng, R. Cheng, J. Zhang*, J. Feijen*, and Z.Y. Zhong*, Highly efficacious and specific anti-glioma chemotherapy by **art tandem nanomicelles co-functionalized with brain tumor-targeting and cell-penetrating peptides, J. Control. Release2018,278, 1-8.

18.  W.J. Yang, Y.F. Xia, Y. Fang, F.H. Meng*, J. Zhang, R. Cheng, C. Deng, and Z.Y. Zhong*, Selective Cell Penetrating Peptide-Functionalized Polymersomes Mediate Efficient and Targeted Delivery of Methotrexate Disodium to Human Lung Cancer In Vivo, Adv. Healthcare Mater.2018, 1701135.

2017

19.  M. Qiu, J. Ouyang, H.L. Sun, F.H. Meng, R. Cheng, J. Zhang, L. Cheng, Q. Lan, C. Deng*, and Z.Y. Zhong*, Biodegradable Micelles Based on Poly(ethylene glycol)-b-Polylipopeptide Copolymer: A Robust and Versatile Nanoplatform for Anticancer Drug Delivery, ACS Appl. Mater. Interfaces2017, 9, 27587-27595.

20.  J. Chen, J. Ouyang, Q.J. Chen, C. Deng*, F.H. Meng, J. Zhang, R. Cheng, Q. Lan, and Z.Y. Zhong*, EGFR and CD44 Dual-Targeted Multifunctional Hyaluronic Acid Nanogels Boost Protein Delivery to Ovarian and Breast Cancers In Vitro and In Vivo, ACS Appl. Mater. Interfaces2017, 9, 24140-24147.

21.  J.T. Wu, J. Zhang, C. Deng*, F.H. Meng, R. Cheng, and Z.Y. Zhong*, Robust, Responsive and Targeted PLGA Anticancer Nanomedicines by Combining Reductively Cleavable Surfactant and Covalent Hyaluronic Acid Coating, ACS Appl. Mater. Interfaces2017, 9, 3985-3994.

22.  J.T. Wu, C. Deng*, F.H. Meng, J. Zhang, H.L. Sun, and Z.Y. Zhong*, Hyaluronic Acid Coated PLGA Nanoparticulate Docetaxel Effectively Targets and Suppresses Orthotopic Human Lung Cancer, J. Control. Release2017, 259, 76-82.

23.  Y.N. Zhong, F.H. Meng*, C. Deng, X.L. Mao*, and Z.Y. Zhong*, Targeted Inhibition of Human Hematological Cancers In Vivo by Doxorubicin Encapsulated in Smart Lipoic Acid-Crosslinked Hyaluronic Acid Nanoparticles, Drug Delivery 2017, 24, 1482-1490.

24.  Y.Q. Zhu, J. Zhang, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, cRGD/TAT dual-ligand reversibly crosslinked micelles loaded with docetaxel penetrate deeply into tumor tissue and show high antitumor efficacy in vivo, ACS Appl. Mater. Interfaces2017, 9, 35651-35663.

25.  P. Zhong, X.L. Gu, R. Cheng*, C. Deng, F.H. Meng, and Z.Y. Zhong*,αvβ3Integrin-Targeted Micellar Mertansine Prodrug Effectively Inhibits Triple-Negative Breast Cancer In Vivo, Int. J. Nanomed. 2017, 12, 7913-7921.

26.  J. Qiu, R. Cheng*, J. Zhang, H.L. Sun, C. Deng, F.H. Meng, and Z.Y. Zhong*, Glutathione-Sensitive Hyaluronic Acid-Mercaptopurine Prodrug Linked via Carbonyl Vinyl Sulfide: A Robust and CD44-Targeted Nanomedicine for Leukemia, Biomacromolecules 2017, 18, 3207-3214.

27.  K.Q. Wu, R. Cheng*, J. Zhang, F.H. Meng, C. Deng, and Z.Y. Zhong*,Micellar Nanoformulation of Lipophilized Bortezomib: High Drug Loading, Improved Tolerability and Targeted Treatment of Triple Negative Breast Cancer, J. Mater. Chem. B2017, 5, 5658-5667.

28.  P. Zhong, M. Qiu, J. Zhang, H.L. Sun, R. Cheng*, C. Deng, F.H. Meng, and Z.Y. Zhong*, cRGD-Installed Docetaxel-Loaded Mertansine Prodrug Micelles: Redox-Triggered Ratiometric Dual Drug Release and Targeted Synergistic Treatment of B16F10 Melanoma, Nanotechnology 2017, 28, 295103.

29.  Y. Fang, Y. Jiang, Y. Zou, F.H. Meng*, J. Zhang, C. Deng, H.L. Sun and Z.Y. Zhong*, Targeted glioma chemotherapy by cyclic RGD peptide-functionalized reversibly core-crosslinked multifunctional poly(ethylene glycol)-b-poly(e-caprolactone) micelles, Acta Biomaterialia 2017, 50, 396-406.

30.  Y.Q. Zhu, X.X. Wang, J. Zhang, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, Exogenous vitamin C boosts the antitumor efficacy of paclitaxel containing reduction-sensitive shell-sheddable micelles in vivo, J. Control. Release2017, 250, 9-19. 

2016

31.  J. Chen, Y. Zou, C. Deng*, F.H. Meng, J. Zhang, and Z.Y. Zhong*, Multifunctional Click Hyaluronic Acid Nanogels for Targeted Protein Delivery and Effective Cancer Treatment In Vivo, Chem. Mater.2016, 28, 8792-8799.

32.  P. Zhong, J. Zhang, C. Deng, R. Cheng*, F.H. Meng, and Z.Y. Zhong*, Glutathione-Sensitive Hyaluronic Acid-SS-Mertansine Prodrug with a High Drug Content: Facile Synthesis and Targeted Breast Tumor Therapy, Biomacromolecules 2016, 17, 3602-3608.

33.  Y.N. Zhong, M. Dimde, D. Stöbener, F.H. Meng*, C. Deng, Z.Y. Zhong*, and R. Haag, Micelles with Sheddable Dendritic Polyglycerol Sulfate Shells Show Extraordinary Tumor Targetability and Chemotherapy In Vivo, ACS Appl. Mater. Interfaces2016, 8, 27530-27538.

34.  W.J. Yang, Y. Zou, F.H. Meng*, J. Zhang, R. Cheng, C. Deng, and Z.Y. Zhong*, Efficient and targeted suppression of human lung tumor xenografts in mice with methotrexate sodium encapsulated in all-function-in-one chimaeric polymersomes, Adv. Mater.2016, 28, 8234-8239.

35.  Y.Q. Zhu, X.X. Wang, J. Chen, J. Zhang, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, Bioresponsive and fluorescent hyaluronic acid-iodixanol nanogels for targeted X-ray computed tomography imaging and chemotherapy of breast tumors, J. Control. Release2016, 244, 229-239.

36.  Y. Zou, F.H. Meng*, C. Deng, and Z.Y. Zhong*, Robust, tumor-homing and redox-sensitive polymersomal doxorubicin: A superior alternative to Doxil and Caelyx? J. Control. Release2016, 239, 149-158.

37.  S. Li, J. Zhang, C. Deng*, F.H. Meng, L. Yu, and Z.Y. Zhong*, Redox-Sensitive and Intrinsically Fluorescent Photoclick Hyaluronic Acid Nanogels for Traceable and Targeted Delivery of Cytochrome C to Breast Tumor In Mice, ACS Appl. Mater. Interfaces2016, 8, 21155-21162.

38.  B.F. Sun, C. Deng*, F.H. Meng, J. Zhang, and Z.Y. Zhong*, Robust, Active Tumor-Targeting and Fast Bioresponsive Anticancer Nanotherapeutics Based on Natural Endogenous Materials, Acta Biomaterialia 2016, 45, 223-233.

39.  J.T. Wu, J. Zhang, C. Deng*, F.H. Meng, and Z.Y. Zhong*, Vitamin E-Oligo(methyl diglycol L-glutamate) as a Biocompatible and Functional Surfactant for Facile Preparation of Active Tumor-Targeting PLGA Nanoparticles, Biomacromolecules 2016, 17, 2367-2374.

40.  Y. Zou, H. Meng, F.H. Meng*, C. Deng, J. Zhang, and Z.Y. Zhong*, Self-crosslinkable and intracellularly decrosslinkable biodegradable micellar nanoparticles: a robust, simple and multifunctional nanoplatform for high-efficiency targeted cancer chemotherapy, J. Control. Release2016, 244, 326-335.

41.  Y.Q. Zhu, J. Zhang*, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, cRGD-functionalized reduction-sensitive shell-sheddable biodegradable micelles mediate enhanced doxorubicin delivery to human glioma xenografts in vivo, J. Control. Release2016, 233, 29-38.

42.  X.X. Wang, J. Zhang, R. Cheng*, F.H. Meng, C. Deng, and Z.Y. Zhong*, Facile synthesis of reductively degradable biopolymers using cystamine diisocyanate as a coupling agent, Biomacromolecules 2016, 17, 882-890.

43.  Y.N. Zhong, K. Goltsche, L. Cheng, F. Xie, F.H. Meng*, C. Deng, Z.Y. Zhong*, and R. Haag, Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo, Biomaterials2016, 84, 250-261. 

2015

44.  X. Li, W.J. Yang, Y. Zou, F.H. Meng*, C. Deng, and Z.Y. Zhong*, Efficacious delivery of protein drugs to prostate cancer cells by PSMA-targeted pH-responsive chimaeric polymersomes, J. Control. Release2015, 220, 704-714.

45.  W.T. Lu, X.X. Wang, R. Cheng*, C. Deng, F.H. Meng, and Z.Y. Zhong*, Biocompatible and Bioreducible Micelles Fabricated from Novel α–Amino Acid-Based Poly(Disulfide Urethane)s: Design, Synthesis and Triggered Doxorubicin Release, Polym. Chem. 2015, 6, 6001-6010.

46.  W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Facile Construction of Dual-Bioresponsive Biodegradable Micelles with Superior Extracellular Stability and Activated Intracellular Drug Release, J. Control. Release2015, 210, 125-133.

47.  W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Biodegradable Glycopolymer-b-Poly(ε-caprolactone) Block Copolymer Micelles: Versatile Construction, Tailored Lactose Functionality, and Hepatoma-Targeted Drug Delivery, J. Mater. Chem. B2015, 3, 2308-2317.

48.  P.P. Chen, M. Qiu, C. Deng*, F.H. Meng, J. Zhang, R. Cheng, and Z.Y. Zhong*, pH-Responsive Chimaeric Pepsomes Based on Asymmetric Poly(ethylene glycol)-b- Poly(L-leucine)- b-Poly(L-glutamic acid) Triblock copolymer for Efficient Loading and Active Intracellular Delivery of Doxorubicin Hydrochloride, Biomacromolecules2015, 16, 1322-1330.

49.  H.L. Sun, R. Cheng, C. Deng, F.H. Meng*, A.A. Dias, M. Hendriks, J. Feijen, and Z.Y. Zhong*, Enzymatically and Reductively Degradable a-Amino Acid-Based Poly(ester amide)s: Synthesis, Cell Compatibility, and Intracellular Anticancer Drug Delivery, Biomacromolecules2015, 16, 597-605.

50.  Y.N. Zhong, J. Zhang, R. Cheng*, C. Deng, F.H. Meng, F. Xie*, and Z.Y. Zhong*, Reversibly Crosslinked Hyaluronic Acid Nanoparticles for Active Targeting and Intelligent Delivery of Doxorubicin to Drug Resistant CD44+ Human Breast Tumor Xenografts, J. Control. Release2015, 205, 144-154.

51.  G.H. Xu, X.L. Wang, C. Deng*, X.M. Teng, E.J. Suuronen, Z.Y. Shen*, and Z.Y. Zhong*, Injectable Biodegradable Hybrid Hydrogels Based on Thiolated Collagen and Oligo(acryloyl carbonate)-Poly(ethylene glycol)-Oligo(acryloyl carbonate) Copolymer for Functional Cardiac Regeneration, Acta Biomaterialia 2015, 15, 55-64.

52.  N.J.R. Blackburn, T. Sofrenovic, D. Kuraitis, A. Ahmadi, B. McNeill, C. Deng, K.J. Rayner, Z.Y. Zhong, M. Ruel, and E.J. Suuronen*, Timing underpins the benefits associated with injectable collagen biomaterial therapy for the treatment of myocardial infarction, Biomaterials2015, 39, 182-192. 

2014

53.  W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Advanced Drug and Gene Delivery Systems Based on Functional Biodegradable Polycarbonates and Copolymers, J. Control. Release2014, 190, 398-414.

54.  Y.N. Zhong, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Ligand-Directed Active Tumor-Targeting Polymeric Nanoparticles for Cancer Chemotherapy, Biomacromolecules2014, 15, 1955-1969.

55.  Y.J. Jiang, J. Chen, C. Deng*, E. Suuronen, and Z.Y. Zhong*, Click Hydrogels, Microgels and Nanogels: Emerging Platforms for Drug Delivery and Tissue Engineering, Biomaterials 2014, 35, 4969-4985.

56.  C. Deng, J.T. Wu, R. Cheng, F.H. Meng, H.A. Klok, and Z.Y. Zhong*, Functional Polypeptide and Hybrid Materials: Precision Synthesis via α-Amino Acid N-Carboxyanhydride Polymerization and Emerging Biomedical Applications, Prog. Polym. Sci.2014, 39, 330-364.

57.  W. Chen, Y. Zou, F.H. Meng, R. Cheng, C. Deng*, J. Feijen, and Z.Y. Zhong*, Glyco-nanoparticles with sheddable saccharide shells: A unique and potent platform for hepatoma-targeting delivery of anticancer drugs, Biomacromolecules2014, 15, 900-907.

58.  H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Reduction and pH dual-bioresponsive crosslinked polymersomes for efficient intracellular delivery of proteins and potent induction of cancer cell apoptosis, Acta Biomaterialia 2014, 10, 2159-2168

59.  F.H. Meng, Y.N. Zhong, R. Cheng, C. Deng, and Z.Y. Zhong*, pH-Sensitive polymeric nanoparticles for tumor-targeting doxorubicin delivery: Concept and recent advances, Nanomedicine2014, 9, 487-499. (invited review)

60.  H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Reduction-Responsive Polymeric Micelles and Vesicles for Triggered Intracellular Drug Release, Antioxidants & Redox Signaling 2014, 21, 755-767. (invited forum article)

61.  W.W. Guo, M. Zheng, Y.N. Zhong, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Poly(ethylene oxide)-graft-methotrexate Macromolecular Drugs Conjugating via Aminopteridine Ring Exhibit Potent Anticancer Activity, Chinese Journal of Chemistry2014, 32, 57-65. 

2013

62.  Y.N. Zhong, W.J. Yang, H.L. Sun, R. Cheng, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Ligand-Directed Reduction-Sensitive Shell-Sheddable Biodegradable Micelles Actively Deliver Doxorubicin into the Nuclei of Target Cancer Cells, Biomacromolecules2013, 14, 3723-3730.

63.  J.R. Zhou, P.P. Chen, C. Deng*, F.H. Meng, R. Cheng, and Z.Y. Zhong*, A Simple and Versatile Synthetic Strategy to Functional Polypeptides via Vinyl Sulfone-Substituted L-Cysteine N-Carboxyanhydride, Macromolecules2013, 46, 6723–6730.

64.  Y.P. Fan, C. Deng*, R. Cheng, F.H. Meng, and Z.Y. Zhong*, In Situ Forming Hydrogels via Catalyst-Free and Bioorthogonal “Tetrazole–Alkene” Photo-Click Chemistry, Biomacromolecules2013, 14, 2814-2821.

65.  X.Y. Wang, H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Galactose-Decorated Reduction-Sensitive Degradable Chimaeric Polymersomes as a Multifunctional Nanocarrier To Efficiently Chaperone Apoptotic Proteins into Hepatoma Cells, Biomacromolecules2013, 14, 2873-2882.

66.  Y.D. Gu, Y.N. Zhong, F.H. Meng*, R. Cheng, C. Deng, andZ.Y. Zhong*, Acetal-Linked Paclitaxel Prodrug Micellar Nanoparticles as a Versatile and Potent Platform for Cancer Therapy, Biomacromolecules2013, 14, 2772-2780.

67.  L.L. Wu, Y. Zou, C. Deng*, R. Cheng, F.H. Meng, and Z.Y. Zhong*, Intracellular Release of Doxorubicin from Core-Crosslinked Polypeptide Micelles Triggered by Both pH and Reduction Conditions, Biomaterials2013, 34, 5262-5272. 

2012 and Before

68.  C. Deng, Y.J. Jiang, R. Cheng, F.H. Meng, and Z.Y. Zhong*, Biodegradable Polymeric Micelles for Targeted and Controlled Anticancer Drug Delivery: Promises, Progress and Prospects. Nano Today2012, 7, 467-480.

69.  Y.X. Yu,C. Deng, F.H. Meng, Q. Shi, J. Feijen, and Z.Y. Zhong*, Novel Injectable Biodegradable Glycol Chitosan-Based Hydrogels Crosslinked by Michael-Type Addition Reaction with Oligo(acryloyl carbonate)-b-Poly(ethylene glycol)-b-Oligo(acryloyl carbonate) Copolymers, J. Biomed. Mater. Res. Part A, 2011, 99A, 316-326.

70.  H. Yu, C. Deng, H. Tian, T. Lu, X. Chen, and X. Jing*, Chemo-Physical and Biological Evaluation of Poly(L-Lysine)-Grafted Chitosan Copolymers. Macromol. Biosci.2011, 11, 352-361.

71.  C. Deng, P. Zhang, B. Vulesevic, D. Kuraitis, F. Li, A.F. Yang, M. Griffith, M. Ruel, and E.J. Suuronen*, A Collagen-Chitosan Hydrogel for Endothelial Differentiation and Angiogenesis. Tissue Eng. Part A2010, 16, 3099-3109.

72.  C. Deng, F. Li*, J.M. Hackett, S.H. Chaudhry, F.N. Toll, B. Toye, W. Hodge, and M. Griffith*, Collagen and Glycopolymer Based Hydrogel for Potential Corneal Application. Acta Biomater.2010, 6, 187-194.

73.  C. Deng, F. Li, M. Griffith, M. Ruel, and E.J. Suuronen*, Application of Chitosan-Based Biomaterials for Blood Vessel Regeneration. Macromolecular Symposia2010,297,138-146.

74.  W. Liu, C. Deng (co-first author), C.R. McLaughlin, P. Fagerholm, N.S. Lagali, B. Heyne, J.C. Scaiano, M.A. Watsky, Y. Kato, R. Munger, N. Shinozaki, F. Li, and M. Griffith*, Collagen-Phosphorylcholine Interpenetrating Network Hydrogels as Corneal Substitutes. Biomaterials2009, 30, 1551-1559.

75.  C. Deng, X. Chen, H. Yu, J. Sun, T. Lu, and X. Jing*, A Biodegradable Triblock Copolymer Poly(ethylene glycol)-b-Poly(L-lactide)-b-Poly(L-lysine): Synthesis, Self-Assembley, and RGD Peptide Modification. Polymer2007, 48, 139-149.

76.  C. Deng, X. Chen, J. Sun, T. Lu, W. Wang, and X. Jing*, RGD Peptide Grafted Biodegradable Amphiphilic Triblock Copolymer Poly(Glutamic Acid)-b- Poly(L-Lactide)-b-Poly(Glutamic Acid): Synthesis and Self-Assembly. J. Polym. Sci. Part A: Polym Chem. 2007, 45, 3218-3230.

77.  J. Sun, C. Deng, X. Chen, H. Yu, H. Tian, J. Sun, and X. Jing*, Self-Assembly of Polypeptide-Containing ABC-Type Triblock Copolymers in Aqueous Solution and Its pH Dependence. Biomacromolecules2007, 8, 1013-1017.

78.  J. Sun, X. Chen, C. Deng, H. Yu, Z. Xie, X. Jing*, Direct Formation of Giant Vesicles From Synthetic Polypeptides. Langmuir2007, 23, 8308-8315.

79.  C. Deng, H.Y. Tian, P.B. Zhang, J. Sun, X.S. Chen, and X.B. Jing*. Synthesis and Characterization of RGD Peptide Grafted Poly(ethylene glycol)-b-Poly(L-lactide)-b-Poly (L-glutamic acid) Triblock Copolymer. Biomacromolecules2006,7,590-596.

80.  C. Deng, G.Z. Rong, H.Y. Tian, Z.H. Tang, X.S. Chen*, and X.B. Jing. Synthesis and Characterization of Poly(ethylene glycol)-b-Poly(L-lactide)-b-Poly(L-glutamic acid) Triblock Copolymer. Polymer2005,46,653-659.


授权专利

1.   邓超,孟凤华,程茹,钟志远,乙烯砜取代的半胱氨酸-N-羧基内酸酐、其聚合物及聚合物的应用,授权专利号:ZL 2013 1 0206285.X,授权公告日:2015年3月25日。

2.   邓超、范亚萍、孟凤华、程茹、钟志远 ,一种水凝胶、其制备方法及应用 ,江苏, 中华人民共和国国家产权局, 授权专利号:ZL 2013 1 0274019.0,授权公告日:2015年4月29日。

3.   邓超,武金田,孟凤华,钟志远,基于聚氨基酸的功能性生物可降解纳米粒子的制备方法,授权专利号:ZL 2016 1 0307271.0,授权公告日:2018年9月21日。

4.   邓超,武金田,孟凤华,钟志远,基于疏水功能性小分子-亲水聚氨基酸生物可降解聚合物及其制备方法和应用,授权专利号:ZL 2016 1 0307256.6,授权公告日:2018年1月19日。

5.   邓超,陈景,孟凤华,钟志远,一种抗癌药物的制备方法,授权专利号:ZL 2016 1 0536411.1,授权公告日:2019年2月19日。

6.   邓超,陈景,孟凤华,钟志远,一种自发荧光纳米凝胶及其制备方法与应用,授权专利号:ZL 2016 1 0536475.1,授权公告日:2019年2月26日。

7.   邓超,邱敏,钟志远,基于2-氨基十六烷酸的N-羧基内酸酐单体和聚氨基酸及其制备方法,授权专利号:ZL 2017 1 0517904.5,授权公告日:2019年8月13日。