固定成员
当前位置:首页 > 科研团队 > 固定成员
程亮 副教授

程亮,博士,副教授。2010年上海交通大学获博士学位(导师郭圣荣教授),同年10月加入苏州大学药学院药剂教研室工作,2012年加入苏州大学生物医用高分子材料实验室从事博士后研究(指导导师钟志远教授),2014年受聘为苏州大学副教授。在国际主流期刊上发表论文20多篇。主持1项国家自然科学青年基金和1项江苏省自然科学青年基金。现阶段的研究工作致力于构建智能聚合物纳米载体,以实现对肝癌的高效靶向治疗。

代表性著作 

1. Hu W, Qiu L, Cheng L, Hu Q, Liu Y, Hu Z, et al. Redox and pH dual responsive poly(amidoamine) dendrimer-poly(ethylene glycol) conjugates for intracellular delivery of doxorubicin. Acta Biomaterialia 2016;36:241-253.

2. Qiu L, Hu Q, Cheng L, Li L, Tian C, Chen W, et al. cRGDyK modified pH responsive nanoparticles for specific intracellular delivery of doxorubicin. Acta Biomaterialia 2016;30:285-298.

3. Zhong Y, Goltsche K, Cheng L, Xie F, Meng F, Deng C, et al. Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo. Biomaterials 2016;84:250-261.

4. Cheng L, Hu Q, Cheng L, Hu W, Xu M, Zhu Y, et al. Construction and evaluation of PAMAM–DOX conjugates withsuperior tumor recognition and intracellular acid-triggered drug release properties. Colloids and Surface B: Biointerfaces 2015;136:37-45.

5. Hu W, Cheng L, Cheng L, Zheng M, Lei Q, Hu Z, et al. Redox and pH-responsive Poly (amidoamine) dendrimer-poly (ethylene glycol) conjugates with disulfide linkages for efficient intracellular drug release. Colloids and Surface B: Biointerfaces 2014;123:254-263.

6. Zhu Y, Cheng L (co-first author), Cheng L, Huang F, Hu Q, Li L, et al. Folate and TAT Peptide Co-Modified Liposomes Exhibit Receptor-Dependent Highly Efficient Intracellular Transport of Payload In Vitro and In Vivo. Pharmaceutical Research 2014;31:3289-3303.

7. Cheng L, Huang F, Cheng L, Zhu Y, Hu Q, Li L, et al. GE11-modified liposomes for non-small cell lung cancer targeting: preparation, ex vitro and in vivo evaluation. International Journal of Nanomedicine. 2014;9:921-935.

8. Wei R, Cheng L, Zheng M, Cheng R, Meng F, Deng C, et al. Reduction-Responsive Disassemblable Core-Cross-Linked Micelles Based on Poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide)−Lipoic Acid Conjugates for Triggered Intracellular Anticancer Drug Release. Biomacromolecules 2012;13: 2429-2438.

9. Lei L, Cheng L, Hou J, Guo S, Zhu C, Shi Y, et al. Prevention of Schistosoma japonicum infection in mice with long-acting praziquantel implants. Experimental Parasitology 2012;131:442-447.

10. Cheng L, Lei L, Guo S, Zhu C, Rong H, Guo D, et al. Schistosoma japonicum: Treatment of different developmental stages in mice with long-acting praziquantel implants. Experimental Parasitology 2011;129(3):254-259..

11. Hou J, Li C, Cheng L, Guo S, Zhang Y, Tang T. Study on hydrophilic 5-fluorouracil release from hydrophobic poly(epsilon-caprolactone) cylindrical implants. Drug Development and Industrial Pharmacy 2011;37(9):1068-1075.

12. Cheng L, Lei L, Guo S. In vitro and in vivo evaluation of praziquantel loaded implants based on PEG/PCL blends. International Journal of Pharmaceutics 2010;387:129-138.

13. Li C, Cheng L (co-first author), Guo S, Wu W. Effects of implant diameter, drug loading and end-capping on praziquantel release from PCL implants. International Journal of Pharmaceutics 2010;386:23-29.

14. Cheng L, Guo S, Wu W. Characterization and in vitro release of praziquantel from poly(ε-caprolactone) implants. International Journal of Pharmaceutics 2009;377:112-119.

15. Yang H, Cheng L, Guo S. Study on acicular poly(ε-caprolactone) implants containing 5-fluorouracil. Chinese Pharmaceutical Journal 2009;44:602-606.

16. Wang S, Guo S, Cheng L. Disodium norcantharidate loaded poly(ε-caprolactone) microspheres: I. Preparation and evaluation. International Journal of Pharmaceutics 2008;350(1-2):130-137.

返回