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孙欢利 副教授

孙欢利,博士,副教授。2013年苏州大学获博士学位,2011年1-2月在荷兰帝斯曼公司培训学习。2013-2015年澳大利亚墨尔本大学博士后,2015年受聘为苏州大学副教授。在国际主流期刊发表论文20余篇,被引用800多次。现负责主持一项国家自然科学青年基金项目和一项江苏省自然科学青年基金项目。主要研究方向为单克隆抗体及多糖介导的多功能性纳米药物用于癌症的靶向治疗。

代表性著作

1. H.L. Sun, E.H.H. Wong, Y. Yan, J.W. Cui, Q. Dai, J.L. Guo, G.G. Qiao, F. Caruso, The Role of Capsule Stiffness on Cellular Processing. Chemical Science, 2015, 6, 3505-3514.

2. H.L. Sun, M. Björnmalm, J.W. Cui, E.H.H. Wong, Y.L. Dai, Q. Dai, G.G. Qiao, F. Caruso, Structure Governs the Deformability of Polymer Particles in a Microfluidic Blood Capillary Model. ACS Macro Letters 2015, 4, 1205-1209.

3. H.L. Sun, R. Cheng, C. Deng, F.H. Meng, A.A. Dias, M. Hendriks, J. Feijen, Z.Y. Zhong, Enzymatically and Reductively Degradable α-Amino Acid-Based Poly(ester amide)s: Synthesis, Cell Compatibility, and Intracellular Anticancer Drug Delivery. Biomacromolecules 2015, 16, 597-605.

4. H.L. Sun, F.H. Meng, R. Cheng, C. Deng, Z.Y. Zhong, Reduction-Responsive Polymeric Micelles and Vesicles for Triggered Intracellular Drug Release. Antioxidant and Redox Signaling 2014, 21, 755-767.

5. H.L. Sun, F.H. Meng, R. Cheng, C. Deng, Z.Y. Zhong, Reduction and pH Dual-Bioresponsive Crosslinked Polymersomes for Efficient Intracellular Delivery of Proteins and Potent Induction of Cancer Cell Apoptosis. Acta Biomaterialia 2014, 10, 2159-2168.

6. H.L. Sun, F.H. Meng, R. Cheng, C. Deng, Z.Y. Zhong, Reduction-Sensitive Degradable Mi-cellar Nanoparticles as Smart and Intuitive Delivery Systems for Cancer Chemotherapy. Expert Opinion on Drug Delivery 2013, 10, 1109-1122.

7. H.L. Sun, F.H. Meng, R. Cheng, C. Deng, Z.Y. Zhong. Reversibly Crosslinked pH Sensitive Polymersomes for Efficient Intracellular Protein Delivery. Journal of Controlled Release 2013, 172, e104.

8. W. Wang, H.L. Sun (co-first author), F.H. Meng, S.B. Ma, H.Y. Liu, Z.Y. Zhong, Precise Control of Intracellular Drug Release and Anti-Tumor Activity of Biodegradable Micellar Drugs via Reduction-Sensitive Shell-Shedding. Soft Matter 2012, 8, 3949-3956.

9. H.L. Sun, F.H. Meng, A.A. Dias, M. Hendriks, J. Feijen, Z.Y. Zhong, α-Amino Acid Containing Degradable Polymers as Functional Biomaterials: Rational Design, Synthetic Pathway, and Biomedical Applications. Biomacromolecules 2011, 12, 1937-1955.

10. H.L. Sun, B.N. Guo, R. Cheng, F.H. Meng, H.Y. Liu, Z.Y. Zhong, Reduction-Responsive Shell-Sheddable Biodegradable Micelles for Intracellular Doxorubicin Delivery. Journal of Controlled Release 2011, 152, e84-85.

11. H.L. Sun, B.N. Guo, X.Q. Li, R. Cheng, F.H. Meng, H.Y. Liu, Z.Y. Zhong, Shell-Sheddable Mi-celles based on Dextran-SS-Poly(ε-caprolactone) Diblock Copolymer for Efficient Intracellular Release of Doxorubicin. Biomacromolecules 2010, 11, 848-854.

12. H.L. Sun, B.N. Guo, R. Cheng, F.H. Meng, H.Y. Liu, Z.Y. Zhong, Biodegradable Micelles with Sheddable Poly(ethylene glycol) Shells for Triggered Intracellular Release of Doxorubicin. Biomaterials 2009, 30, 6358-6366.

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