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  • 2017

    111. J.T. Wu, J. Zhang, C. Deng*, F.H. Meng, R. Cheng, and Z.Y. Zhong*, Robust, Responsive and Targeted PLGA Anticancer Nanomedicines by Combining Reductively Cleavable Surfactant and Covalent Hyaluronic Acid Coating, ACS Appl. Mater. Interfaces 2017, DOI: 10.1021/acsami.6b15105   111.pdf

    110. Y. Fang, Y. Jiang, Y. Zou, F.H. Meng*, J. Zhang, C. Deng, H.L. Sun and Z.Y. Zhong*, Targeted glioma chemotherapy by cyclic RGD peptide-functionalized reversibly core-crosslinked multifunctional poly(ethylene glycol)-b-poly(e-caprolactone) micelles, Acta Biomaterialia 2017, http://dx.doi.org/10.1016/j.actbio.2017.01.007   110.pdf

    109. J.T. Wu, C. Deng*, F.H. Meng, J. Zhang, H.L. Sun, and Z.Y. Zhong*, Hyaluronic acid coated PLGA nanoparticulate docetaxel effectively targets and suppresses orthotopic human lung cancer, J. Control. Release 2017,  http://dx.doi.org/10.1016/j.jconrel.2016.12.024   109.pdf.pdf

    108. P. Zhong, H. Meng, J. Qiu, J. Zhang, H.L. Sun, R. Cheng*, and Z.Y. Zhong*,αvβ3 Integrin-Targeted Reduction-Sensitive Micellar Mertansine Prodrug: Superb Drug Loading, Enhanced Stability, and Effective Inhibition of Melanoma Growth In Vivo, J. Control. Release 2017,  DOI: 10.1016/j.jconrel.2016.12.011   108.pdf

    107. Y. Zou, Y.H. Wei, G.L. Wang, F.H. Meng*, M.Y. Gao, G. Storm, and Z.Y. Zhong*, Nano-Polymersomes with an Ultrahigh Iodine Content for High-Performance X-Ray Computed Tomography Imaging In Vivo, Adv. Mater. 2017, http://dx.doi.org/10.1002/adma.201603997   107.pdf

    106. W. Chen, Y. Zou, Z.Y. Zhong*, and R. Haag *, Cyclo(RGD)-decorated Redox-responsive Nanogels Mediate Targeted Chemotherapy of Integrin Over-expressing Human Glioblastoma In Vivo, Small 2017, DOI: 10.1002/smll.201601997   106.pdf

    105. N. Zhang, Y.F. Xia, Y. Zou, W.J. Yang, J. Zhang, Z.Y. Zhong*, and F.H. Meng*, ATN-161 Peptide Functionalized Reversibly Crosslinked Polymersomes Mediate Targeted Doxorubicin Delivery into Melanoma-Bearing C57BL/6 Mice, Mol. Pharm. 2017, DOI: 10.1021/acs.molpharmaceut.6b00800   105.pdf



  • 2016

    104. J. Chen, Y. Zou, C. Deng*, F.H. Meng, J. Zhang, and Z.Y. Zhong*, Multifunctional Click Hyaluronic Acid Nanogels for Targeted Protein Delivery and Effective Cancer Treatment In Vivo, Chem. Mater. 2016, 28, 8792-8799.    104.pdf

    103. P. Zhong, J. Zhang, C. Deng, R. Cheng*, F.H. Meng, and Z.Y. Zhong*, Glutathione-Sensitive Hyaluronic Acid-SS-Mertansine Prodrug with a High Drug Content: Facile Synthesis and Targeted Breast Tumor Therapy, Biomacromolecules 2016, 17, 3602-3608.   103.pdf

    102. Y.N. Zhong, M. Dimde, D. Stöbener, F.H. Meng*, C. Deng, Z.Y. Zhong*, and R. Haag, Micelles with Sheddable Dendritic Polyglycerol Sulfate Shells Show Extraordinary Tumor Targetability and Chemotherapy In Vivo, ACS Appl. Mater. Interfaces 2016, 8, 27530-27538.   102.pdf

    101. W.J. Yang, Y. Zou, F.H. Meng*, J. Zhang, R. Cheng, C. Deng, and Z.Y. Zhong*, Efficient and targeted suppression of human lung tumor xenografts in mice with methotrexate sodium encapsulated in all-function-in-one chimaeric polymersomes, Adv. Mater. 2016, 28, 8234-8239.   101.pdf

    100. Y.Q. Zhu, X.X. Wang, J. Chen, J. Zhang, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, Bioresponsive and fluorescent hyaluronic acid-iodixanol nanogels for targeted X-ray computed tomography imaging and chemotherapy of breast tumors, J. Control. Release 2016, 244, 229-239.   100.pdf

    99. Y. Zou, F.H. Meng*, C. Deng, and Z.Y. Zhong*, Robust, tumor-homing and redox-sensitive polymersomal doxorubicin: A superior alternative to Doxil and Caelyx? J. Control. Release 2016, 239, 149-158.   99.pdf

    98. S. Li, J. Zhang, C. Deng*, F.H. Meng, L. Yu, and Z.Y. Zhong*, Redox-sensitive and intrinsically fluorescent photoclick hyaluronic acid nanogels for traceable and targeted delivery of cytochrome C to breast tumor in mice, ACS Appl. Mater. Interfaces 2016, 8, 21155-21162   98.pdf

    97. B.F. Sun, C. Deng*, F.H. Meng, J. Zhang, and Z.Y. Zhong*, Robust, active tumor-targeting and fast bioresponsive anticancer nanotherapeutics based on natural endogenous materials, Acta Biomaterialia 2016, 45, 223-233.   97.pdf

    96. J.T. Wu, J. Zhang, C. Deng*, F.H. Meng, and Z.Y. Zhong*, Vitamin E-Oligo(methyl diglycol L-glutamate) as a Biocompatible and Functional Surfactant for Facile Preparation of Active Tumor-Targeting PLGA Nanoparticles, Biomacromolecules 2016, 17, 2367-2374   96.pdf

    95. Y. Zou, H. Meng, F.H. Meng*, C. Deng, J. Zhang, and Z.Y. Zhong*, Self-crosslinkable and intracellularly decrosslinkable biodegradable micellar nanoparticles: a robust, simple and multifunctional nanoplatform for high-efficiency targeted cancer chemotherapy, J. Control. Release 2016, 244, 326-335.   95.pdf

    94. Y.Q. Zhu, J. Zhang*, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, cRGD-functionalized reduction-sensitive shell-sheddable biodegradable micelles mediate enhanced doxorubicin delivery to human glioma xenografts in vivo, J. Control. Release 2016, 233, 29-38.   94.pdf

    93. X. Ma, Z.W. He, F.X. Han, Z.Y. Zhong*, L. Chen, and B. Li*, Preparation of collagen/hydroxyapatite/alendronate hybrid hydrogels as potential scaffolds for bone regeneration, Colloids Surf. B: Biointerfaces 2016, 143, 81-87.   93.pdf

    92. X.X. Wang, J. Zhang, R. Cheng*, F.H. Meng, C. Deng, and Z.Y. Zhong*, Facile synthesis of reductively degradable biopolymers using cystamine diisocyanate as a coupling agent, Biomacromolecules 2016, 17, 882-890.   92.pdf

    91. Y.N. Zhong, K. Goltsche, L. Cheng, F. Xie, F.H. Meng*, C. Deng, Z.Y. Zhong*, and R. Haag, Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo, Biomaterials 2016, 84, 250-261.   91.pdf


  • 2015


    90. X. Li, W.J. Yang, Y. Zou, F.H. Meng*, C. Deng, and Z.Y. Zhong*, Efficacious delivery of protein drugs to prostate cancer cells by PSMA-targeted pH-responsive chimaeric polymersomes, J. Control. Release 2015, 220, 704-714. 

    89. R. Cheng, F.H. Meng, C. Deng, and Z.Y. Zhong*, Bioresponsive Polymeric Nanotherapeutics for Targeted Cancer Chemotherapy, Nano Today 2015, 10, 656-670.   89.pdf

    88. S.Y. Liu*, and Z.Y. Zhong*,  Preface - Special Topic: Progress in Synthetic Polymer Chemistry, SCIENCECHINAChemistry 2015, 58, 1631-1632.

    87. W.T. Lu, X.X. Wang, R. Cheng*, C. Deng, F.H. Meng, and Z.Y. Zhong*, Biocompatible and Bioreducible Micelles Fabricated from Novel α-Amino Acid-Based Poly(disulfide urethane)s: Design, Synthesis and Triggered Doxorubicin Release, Polymer Chemistry 2015, 6, 6001-6010.   87.pdf

    86. F.S. Huang, R. Cheng*, F.H. Meng, C. Deng, and Z.Y. Zhong*, Micelles Based on Acid Degradable Poly(acetal urethane): Preparation, pH-Sensitivity, and Triggered Intracellular Drug Release, Biomacromolecules 2015, 16, 2228-2236.   86.pdf

    85. L. Lu, Y. Zou, W.J. Yang, F.H. Meng*, C. Deng, R. Cheng, and Z.Y. Zhong*, Anisamide-Decorated pH-Sensitive Degradable Chimaeric Polymersomes Mediate Potent and Targeted Protein Delivery to Lung Cancer Cells, Biomacromolecules 2015, 16, 1726-1735   85.pdf

    84. W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Facile Construction of Dual-Bioresponsive Biodegradable Micelles with Superior Extracellular Stability and Activated Intracellular Drug Release, J. Control. Release 2015, 210, 125-133   84.pdf

    83. Z.Y. Zhong*, Professor Jan Feijen: a Pioneer in Biomedical Polymers and Controlled Drug Release, J. Control. Release 2015, 205, 3-6.   83.pdf

    82. Z.Y. Zhong*, and J. Feijen, The Third Symposium on Innovative Polymers for Controlled Delivery, September 16-19, 2014, Suzhou, China, J. Control. Release 2015, 205, 1-2.   82.pdf

    81. H. He, Y.G. Bai, J.H. Wang, Q.R. Deng, L.P. Zhu, F.H. Meng, Z.Y. Zhong*, and L.C. Yin*, Reversibly crosslinked polyplexes enable cancer-targeted gene delivery via self-promoted DNA release and self-diminished toxicity, Biomacromolecules 2015, 16, 1390-1400.   81.pdf

    80. P.P. Chen, M. Qiu, C. Deng*, F.H. Meng, J. Zhang, R. Cheng, and Z.Y. Zhong*, pH-Responsive Chimaeric Pepsomes Based on Asymmetric Poly(ethylene glycol)-b-Poly(L-leucine)-b-Poly(L-glutamic acid) Triblock Copolymer for Efficient Loading and Active Intracellular  Delivery of Doxorubicin Hydrochloride, Biomacromolecules 2015, 16, 1322-1330.   80.pdf

    79. J.L. Lv, H.L. Sun, Y. Zou, F.H. Meng*, A.A. Dias, M. Hendriks, J. Feijen, and Z.Y. Zhong*, Reductively Degradable a-Amino Acid-Based Poly(ester amide)-Graft-Galactose Copolymers: Facile Synthesis, Self-Assembly, and Hepatoma-Targeting Doxorubicin Delivery, Biomater. Sci. 2015, 3, 1134-1146.   79.pdf

    78. Y.N. Zhong, J. Zhang, R. Cheng*, C. Deng, F.H. Meng, F. Xie*, and Z.Y. Zhong*, Reversibly Crosslinked Hyaluronic Acid Nanoparticles for Active Targeting and Intelligent Delivery of Doxorubicin to Drug Resistant CD44+ Human Breast Tumor Xenografts, J. Control. Release 2015, 205, 144-154.   78.pdf

    77. W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Biodegradable Glycopolymer-b-Poly(e-caprolactone) Block Copolymer Micelles: Versatile Construction, Tailored Lactose Functionality, and Hepatoma-Targeted Drug Delivery, J. Mater. Chem. B 2015, 3, 2308-2317.   77.pdf

    76. H.L. Sun, R. Cheng, C. Deng, F.H. Meng*, A.A. Dias, M. Hendriks, J. Feijen, and Z.Y. Zhong*, Enzymatically and Reductively Degradable a-Amino Acid-Based Poly(ester amide)s: Synthesis, Cell Compatibility, and Intracellular Anticancer Drug Delivery, Biomacromolecules 2015, 16, 597-605.   76.pdf

    75. G.H. Xu, X.L. Wang, C. Deng*, X.M. Teng, E.J. Suuronen, Z.Y. Shen*, and Z.Y. Zhong*, Injectable Biodegradable Hybrid Hydrogels Based on Thiolated Collagen and Oligo(acryloyl carbonate)-Poly(ethylene glycol)-Oligo(acryloyl carbonate) Copolymer for Functional Cardiac Regeneration, Acta Biomaterialia 2015, 15, 55-64.   75.pdf

    74. N.J.R. Blackburn, T. Sofrenovic, D. Kuraitis, A. Ahmadi, B. McNeill, C. Deng, K.J. Rayner, Z.Y. Zhong, M. Ruel, and E.J. Suuronen*, Timing underpins the benefits associated with injectable collagen biomaterial therapy for the treatment of myocardial infarction, Biomaterials 2015, 39, 182-192.   74.pdf

  • 2014


    73. W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Advanced Drug and Gene Delivery Systems Based on Functional Biodegradable Polycarbonates and Copolymers, J. Control. Release 2014, 190, 398-414.   73.pdf

    72. Y.N. Zhong, C. Wang, R. Cheng, L. Cheng, F.H. Meng*, Z. Liu*, and Z.Y. Zhong*, cRGD-Directed, NIR-Responsive and Robust AuNR/PEG-PCL Hybrid Nanoparticles for Targeted Chemotherapy of Glioblastoma In Vivo, J. Control. Release 2014, 195, 63-71.   72.pdf

    71. Y.N. Zhong, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Ligand-Directed Active Tumor-Targeting Polymeric Nanoparticles for Cancer Chemotherapy, Biomacromolecules 2014, 15, 1955-1969.   71.pdf

    70. Y. Zou, Y. Song, W.J. Yang, F.H. Meng*, H.Y.Liu, and Z.Y. Zhong*, Galactose-Installed Photo-Crosslinked pH-Sensitive Degradable Micelles for Active Targeting Chemotherapy of Hepatocellular Carcinoma in Mice, J. Control. Release 2014, 193, 154-161.   70.pdf

    69. Y.J. Jiang, J. Chen, C. Deng*, E. Suuronen, and Z.Y. Zhong*, Click Hydrogels, Microgels and Nanogels: Emerging Platforms for Drug Delivery and Tissue Engineering, Biomaterials  2014, 35, 4969-4985.   69.pdf

    68. C. Deng, J.T. Wu, R. Cheng, F.H. Meng, H.A. Klok, and Z.Y. Zhong*, Functional Polypeptide and Hybrid Materials: Precision Synthesis via α-Amino Acid N-Carboxyanhydride Polymerization and Emerging Biomedical Applications, Prog. Polym. Sci. 2014, 39, 330-364.   68.pdf

    67. W. Chen, Y. Zou, F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Glyco-Nanoparticles with Sheddable Saccharide Shells: A Unique and Potent Platform for Hepatoma-Targeting Delivery of Anticancer Drugs, Biomacromolecules 2014, 15, 900-907.   67.pdf

    66. H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Reduction and pH Dual-Bioresponsive Crosslinked Polymersomes for Efficient Intracellular Delivery of Proteins and Potent Induction of Cancer Cell Apoptosis, Acta Biomaterialia 2014, 10, 2159-2168   66.pdf

    65. F.H. Meng, Y.N. Zhong, R. Cheng, C. Deng, and Z.Y. Zhong*, pH-Sensitive polymeric nanoparticles for tumor-targeting doxorubicin delivery: Concept and recent advances, Nanomedicine 2014, 9, 487-499. (invited review) 

    64. H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Reduction-Responsive Polymeric Micelles and Vesicles for Triggered Intracellular Drug Release, Antioxidants & Redox Signaling 2014, 21, 755-767. (invited forum article)   64.pdf

    63. W.W. Guo, M. Zheng, Y.N. Zhong, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Poly(ethylene oxide)-graft-methotrexate Macromolecular Drugs Conjugating via Aminopteridine Ring Exhibit Potent Anticancer Activity, Chinese Journal of Chemistry 2014, 32, 57-65.   63.pdf


  • 2013


    62. Y.N. Zhong, W.J. Yang, H.L. Sun, R. Cheng, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Ligand-Directed Reduction-Sensitive Shell-Sheddable Biodegradable Micelles Actively Deliver Doxorubicin into the Nuclei of Target Cancer Cells, Biomacromolecules 2013, 14, 3723-3730.   62.pdf

    61. J.R. Zhou, P.P. Chen, C. Deng*, F.H. Meng, R. Cheng, and Z.Y. Zhong*, A Simple and Versatile Synthetic Strategy to Functional Polypeptides via Vinyl Sulfone-Substituted L-Cysteine N-Carboxyanhydride, Macromolecules 2013, 46, 6723–6730.  61.pdf

    60. Y.P. Fan, C. Deng*, R. Cheng, F.H. Meng, and Z.Y. Zhong*, In Situ Forming Hydrogels via Catalyst-Free and Bioorthogonal “Tetrazole–Alkene” Photo-Click Chemistry, Biomacromolecules 2013, 14, 2814-2821.   60.pdf

    59. X.Y. Wang, H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Galactose-Decorated Reduction-Sensitive Degradable Chimaeric Polymersomes as a Multifunctional Nanocarrier To Efficiently Chaperone Apoptotic Proteins into Hepatoma Cells, Biomacromolecules 2013, 14, 2873-2882.   59.pdf

    58. Y.D. Gu, Y.N. Zhong, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Acetal-Linked Paclitaxel Prodrug Micellar Nanoparticles as a Versatile and Potent Platform for Cancer Therapy, Biomacromolecules 2013, 14, 2772-2780.   58.pdf

    57. Y.N. Zhong, W. Wang, L. Cheng,  F.H. Meng, Z.Y. Zhong*, and Z. Liu*, Gold Nanorod-Cored Biodegradable Micelles as a Robust and Remotely Controllable Doxorubicin Release System for Potent Inhibition of Drug-Sensitive and -Resistant Cancer Cells, Biomacromolecules 2013, 14, 2411-2419.

    56. L.L. Wu, Y. Zou, C. Deng*, R. Cheng, F.H. Meng, and Z.Y. Zhong*, Intracellular Release of Doxorubicin from Core-Crosslinked Polypeptide Micelles Triggered by Both pH and Reduction Conditions, Biomaterials 2013, 34, 5262-5272.   56.pdf

    55. W. Chen, M. Zheng, F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, In Situ Forming Reduction-Sensitive Degradable Nanogels for Facile Loading and Triggered Intracellular Release of Proteins, Biomacromolecules 2013, 14, 1214-1222.   55.pdf

    54. H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Reduction-Sensitive Degradable Micellar Nanoparticles as Smart and Intuitive Delivery Systems for Cancer Chemotherapy, Expert Opin. Drug Deliv. 2013, 10, 1109-1122.   54.pdf

    53. R. Cheng, F.H. Meng, C. Deng, H.A. Klok, and Z.Y. Zhong*, Dual and Multi-Stimuli Responsive Polymeric Nanoparticles for Programmed Site-Specific Drug Delivery, Biomaterials 2013, 34, 3647-3657.   53.pdf

    52. J. Feijen, and Z.Y. Zhong*, The Second Symposium on Innovative Polymers for Controlled Delivery, September 11-14, 2012, Suzhou,China, J. Control. Release 2013, 169, 163-164.   52.pdf

    51. W. Chen, P. Zhong, F.H. Meng*, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Redox and pH-Responsive Degradable Micelles for Dually Activated Intracellular Anticancer Drug Release, J. Control. Release 2013, 169, 171-179.   51.pdf

    50. J. Feijen, W.E. Hennink‌, and Z.Y. Zhong*, Conference Scene: From Innovative Polymers To Advanced Nanomedicine: Key Challenges, Recent Progress and Future Perspectives, Nanomedicine 2013, 8, 177-180.   50.pdf

    49. W. Chen, Y. Zou, J.N. Jia, F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Functional Poly(ε-caprolactone)s via Copolymerization of ε‑Caprolactone and Pyridyl Disulfide-Containing Cyclic Carbonate: Controlled Synthesis and Facile Access to Reduction-Sensitive Biodegradable Graft Copolymer Micelles, Macromolecules 2013, 46, 699-707.   49.pdf


  • 2012

    48. F.H. Meng, R. Cheng, C. Deng, and Z.Y. Zhong*, Intracellular Drug Release Nanosystems, Materials Today 2012, 15, 436-442 (invited review)   48.pdf

    47. Y.L. Wu, W. Chen, F.H. Meng, Z.J. Wang, R. Cheng, C. Deng, H.Y. Liu, and Z.Y. Zhong*, Core-Crosslinked pH-Sensitive Degradable Micelles: A Promising Approach to Resolve the Extracellular Stability Versus Intracellular Drug Release Dilemma, J. Control. Release 2012, 164, 338-345.   47.pdf

    46. C. Deng, Y.J. Jiang, R. Cheng, F.H. Meng, and Z.Y. Zhong*, Biodegradable Polymeric Micelles for Targeted and Controlled Anticancer Drug Delivery: Promises, Progress and Prospects, Nano Today 2012, 7, 467-480 (invited review)

    45. R.R. Wei, L. Cheng, M. Zheng, R. Cheng, F.H. Meng, C. Deng, and Z.Y. Zhong*, Reduction-Responsive Disassemblable Core-Cross-Linked Micelles Based on Poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide)–Lipoic Acid Conjugates for Triggered Intracellular Anticancer Drug Release, Biomacromolecules 2012, 13, 2429-2438.   45.pdf

    44. S.K. Li, F.H. Meng, Z.J. Wang, Y.N. Zhong, M. Zheng, H.Y. Liu, and Z.Y. Zhong*, Biodegradable Polymersomes with An Ionizable Membrane: Facile Preparation, Superior Protein Loading, And Endosomal pH-Responsive Protein Release, Eur. J. Pharm. Biopharm. 2012, 82, 103-111 (invited article)   44.pdf

    43. Y.F. Du, W. Chen, M. Zheng, F.H. Meng, and Z.Y. Zhong*, pH-Sensitive Degradable Chimaeric Polymersomes for the Intracellular Release of Doxorubicin Hydrochloride, Biomaterials 2012, 33, 7291-7299.   43.pdf

    42. R. Cheng, X.Y. Wang, W. Chen, F.H. Meng, C. Deng, H.Y. Liu, and Z.Y. Zhong*, Biodegradable Poly(ε-caprolactone)-g-Poly(2-hydroxyethyl methacrylate) Graft Copolymer Micelles as Superior Nano-Carriers for “Smart” Doxorubicin Release, J. Mater. Chem. 2012, 22, 11730-11738.   42.pdf

    41. M. Zheng, Z.H. Zhong, L. Zhou, F.H. Meng, R. Peng, and Z.Y. Zhong*, Poly(ethylene oxide) Grafted with Short Polyethylenimine Gives DNA Polyplexes with Superior Colloidal Stability, Low Cytotoxicity and Potent In Vitro Gene Transfection Under Serum Conditions, Biomacromolecules 2012, 13, 881–888.

    40. W. Wang, H.L. Sun, F.H. Meng, S.B. Ma, H.Y. Liu, and Z.Y. Zhong*, Precise Control of Intracellular Drug Release and Anti-Tumor Activity of Biodegradable Micellar Drugs Via Reduction-Sensitive Shell-Shedding, Soft Matter 2012, 8, 3949-3956.   40.pdf

    39. C.H. Zhu, M. Zheng, F.H. Meng, F.M. Mickler, N. Ruthardt, X.L. Zhu, and Z.Y. Zhong*, Reversibly Shielded DNA Polyplexes Based on Bioreducible PDMAEMA-SS-PEG-SS-PDMAEMA Triblock Copolymers Mediate Markedly Enhanced Nonviral Gene Transfection, Biomacromolecules 2012, 13, 769–778.   39.pdf

    38. J.C. Zhang, L.L. Wu, F.H. Meng, Z.J. Wang, C.Deng, H.Y. Liu, and Z.Y. Zhong*, pH and Reduction Dual-Bioresponsive Polymersomes for Efficient Intracellular Protein Delivery, Langmuir 2012, 28, 2056–2065. (invited article)   38.pdf

    37. M. Zheng, C.M. Yang, F.H. Meng, R. Peng, and Z.Y. Zhong*, pH-Sensitive Degradable Hydrophobe Modified 1.8 kDa Branched Polyethylenimine, as “Artificial Viruses” for Safe and Efficient Intracellular Gene Transfection, Macromol. Res. 2012, 20, 327-334 (Invited Article)   37.pdf


  • 2011

    36. F.X. Zhan, W. Chen, Z.J. Wang, W.T. Lu, R. Cheng, C. Deng, F.H. Meng, H.Y. Liu and Z.Y. Zhong*, Acid-Activatable Prodrug Nanogels for Efficient Intracellular Doxorubicin Release, Biomacromolecules 2011, 12, 3612–3620.   36.pdf

    35. R. Cheng, F.H. Meng, S.B. Ma, H.F. Xu, H.Y. Liu, X.B. Jing, and Z.Y. Zhong*, Reduction and Temperature Dual-Responsive Crosslinked Polymersomes for Targeted Intracellular Protein Delivery, J. Mater. Chem. 2011, 21, 19013-19020.   35.pdf

    34. M. Zheng, Y.N. Zhong, F.H. Meng, R. Peng, and Z.Y. Zhong*, Lipoic Acid Modified Low Molecular Weight Polyethylenimine Mediates Nontoxic and Highly Potent In Vitro Gene Transfection, Mol. Pharmaceutics, 2011, 8, 2434-2443.   34.pdf

    33. Z.Z. Liu, M. Zheng, F.H. Meng, and Z.Y. Zhong*, Non-Viral Gene Transfection In Vitro Using Endosomal pH-Sensitive Reversibly Hydrophobilized Polyethylenimine, Biomaterials 2011, 32, 9109-9119.   33.pdf

    32. R. Wang, W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Unprecedented Access to Functional Biodegradable Polymers and Coatings, Macromolecules 2011, 44, 6009–6016.    32.pdf

    31. Y.H. Cong, H. Liu, D.L. Wang, B.J. Zhao, T.Z. Yan, L.B. Li , W. Chen, Z.Y. Zhong , M.-C. Lin, H.-L. Chen, and C.L. Yang, Stretch-Induced Crystallization through Single Molecular Force Generating Mechanism, Macromolecules 2011, 44, 5878-5882.   31.pdf

    30. J. Chen, W. Chen, C. Deng, F.H. Meng, and Z.Y. Zhong*, Controlled Surface-Initiated Ring-Opening Polymerization of L-Lactide from Risedronate-Anchored Hydroxyapatite Nanocrystals: Novel Synthesis of Biodegradable Hydroxyapatite/Poly(L-lactide) Nanocomposites, J. Polym. Sci. Part  A: Polym. Chem. 2011, 49, 4379-4386.   30.pdf

    29. R. Yang, F.H. Meng, S.B. Ma, F.S. Huang, H.Y. Liu, and Z.Y. Zhong*, Galactose-Decorated Crosslinked Biodegradable Poly(Ethylene Glycol)-b-Poly(ε-Caprolactone) Block Copolymer Micelles for Enhanced Hepatoma-Targeting Delivery of Paclitaxel, Biomacromolecules 2011, 12, 3047–3055.   29.pdf

    28. Y.X. Yu, C. Deng, F.H. Meng, Q. Shi, J. Feijen, and Z.Y. Zhong*, Novel Injectable Biodegradable Glycol Chitosan-Based Hydrogels Crosslinked by Michael-Type Addition Reaction with Oligo(acryloyl carbonate)-b-Poly(ethylene glycol)-b-Oligo(acryloyl carbonate) Copolymers, J. Biomed. Mater. Res. Part A  2011, 99A, 316-326.   28.pdf

    27. S.B. Luo, R. Cheng, F.H. Meng, T.G. Park, and Z.Y. Zhong*, Water Soluble Poly(histamine acrylamide) with Superior Buffer Capacity Mediates Efficient and Nontoxic In Vitro Gene Transfection, J. Polym. Sci. Part  A: Polym. Chem. 2011, 49, 3366–3373.   27.pdf

    26. F.H. Meng, and Z.Y. Zhong*, Polymersomes Spanning from Nano to Micro Scales: Advanced Vehicles for Controlled Drug Delivery and Robust Vesicles for Virus and Cell-Mimicking, J. Phys. Chem. Letters 2011, 2, 1533-1539. (Invited Perspective)   26.pdf

    25. H.L. Sun, F.H. Meng, A.A. Dias, M. Hendriks, J. Feijen, and Z.Y. Zhong*, a-Amino Acid Containing Degradable Polymers as Functional Biomaterials: Rational Design, Synthetic Pathway and Biomedical Applications, Biomacromolecules 2011, 12, 1937-1955.   25.pdf

    24. J. Xiong, F.H. Meng, C. Wang, R. Cheng, Z. Liu, and Z.Y. Zhong*, Folate-Conjugated Crosslinked Biodegradable Micelles for Receptor-Mediated Delivery of Paclitaxel, J. Mater. Chem. 2011, 21, 5786-5794.   24.pdf

    23. L. Zhou, R. Cheng, H.Q. Tao, S.B. Ma, W.W. Guo, F.H. Meng, H.Y. Liu, Z. Liu, and Z.Y. Zhong*, Endosomal pH-Activatable Poly(ethylene oxide)-graft-Doxorubicin Prodrugs: Synthesis, Drug Release, and Biodistribution in Tumor-Bearing Mice, Biomacromolecules 2011, 12, 1460–1467.   23.pdf

    22. Y.H. Wang, M. Zheng, F.H. Meng, J. Zhang, R. Peng, and Z.Y. Zhong*, Branched Polyethylenimine Derivatives with Reductively Cleavable Periphery for Safe and Efficient In Vitro Gene Transfer, Biomacromolecules 2011, 12, 1032-1040.   22.pdf

    21. R. Cheng, F. Feng, F.H. Meng, C. Deng, J. Feijen, Z.Y. Zhong*, Glutathione-Responsive Nano-Vehicles as a Promising Platform for Targeted Intracellular Drug and Gene Delivery, J. Control. Release 2011, 152, 2-12.   21.pdf

    20. Z.Y. Zhong*, and J. Feijen, The First Symposium on Innovative Polymers for Controlled Delivery, September 14-17, 2010, Suzhou, China, J. Control. Release 2011, 152, 1-1.   20.pdf

    19. G.J. Liu, S.B. Ma, S.K. Li, R. Cheng, F.H. Meng,*, H.Y. Liu, Z.Y. Zhong*, The highly efficient delivery of exogenous proteins into cells mediated by biodegradable chimaeric polymersomes, Biomaterials 2010, 31, 7575-7585.   19.pdf


  • 2010 

    18. R. Jin, L.S. MoreiraTeixeira,  P.J. Dijkstra, Z.Y. Zhong, C.A. van Blitterswijk, M. Karperien, J. Feijen, Enzymatically crosslinked dextran-tyramine hydrogels as injectable scaffolds for cartilage tissue engineering, Tissue Engineering Part A. 2010,16, 2429-2440. 

    17. C.H. Zhu, S.Y. Jung, G.Y. Si, R. Cheng, F.H. Meng*, X.L. Zhu, T.G. Park, and Z.Y. Zhong*, Cationic methacrylate copolymers containing primary and tertiary amino side groups: controlled synthesis via RAFT polymerization, DNA condensation, and in vitro gene transfection, J. Polym. Sci. Part  A: Polym. Chem.  2010, 48, 2869–2877.   17.pdf

    16. H.L. Sun, F.H. Meng*, B.N. Guo, X.Q. Li, R. Cheng, H.Y. Liu, and Z.Y. Zhong*, Shell-sheddable micelles based on dextran-ss-poly(e-caprolactone) diblock copolymer for efficient intracellular release of doxorubicin, Biomacromolecules 2010, 11, 848–854.   16.pdf

    15. R. Namgung, J.H. Brumbach, J.H. Jeong, J.W. Yockman, S.W. Kim, C. Lin, Z.Y. Zhong, J. Feijen, J.F.J. Engbersen, and W.J. Kim*,  Dual bio-responsive gene delivery via reducible poly(amido amine) and survivin-inducible plasmid DNA, Biotechnol. Lett. 2010, 32, 755-764.   15.pdf

    14. C.H. Zhu, S.Y. Jung, S.B. Luo, F.H. Meng, X.L. Zhu, T.G. Park, and Z.Y. Zhong*, Co-delivery of siRNA and Paclitaxel into Cancer Cells by Biodegradable Cationic Micelles Based on PDMAEMA-PCL-PDMAEMA Triblock Copolymers, Biomaterials 2010, 31, 2408–2416.   14.pdf

    13. W. Chen, F.H. Meng*, R. Cheng, and Z.Y. Zhong*, pH-Sensitive Degradable Polymersomes for Triggered Release of Anticancer Drugs: a Comparative Study with Micelles, J. Control. Release 2010, 142, 40-46.  13.pdf

    12. W. Chen, H.C. Yang, R. Wang, R. Cheng, F.H. Meng*, W.X. Wei, and Z.Y. Zhong*, Versatile Synthesis of Functional Biodegradable Polymers by Combining Ring-Opening Polymerization and Postpolymerization Modification via Michael-Type Addition Reaction, Macromolecules 2010, 43, 201–207.   12.pdf

    11. J.M. Jukes, L.J. van der Aa, C. Hiemstra, T. van Veen, P.J. Dijkstra, Z.Y. Zhong, J. Feijen, C.A. van Blitterswijk, J. de Boer, A newly developed chemically crosslinked Dex-PEG hydrogel for cartilage tissue engineering, Tissue Engineering Part A. 2010, 16: 565-573.   11.pdf


  • 2009

    10. Y.L. Li, L. Zhu, Z.Z. Liu, R. Cheng, F.H. Meng*, J.H. Cui, S.J. Ji, and Z.Y. Zhong*, Reversibly Stabilized Multifunctional Dextran Nanoparticles Efficiently Deliver Doxorubicin into the Nuclei of Cancer Cells, Angew. Chem. Int. Ed. 2009, 48, 9914-9918.   10.pdf

    9. Y.M. Xu, F.H. Meng*, R. Cheng, Z.Y. Zhong*, Reduction-Sensitive Reversibly Crosslinked Biodegradable Micelles for Triggered Release of Doxorubicin, Macromol. Biosci. 2009, 9, 1254-1261.   9.pdf

    8. H.Z. Du, A.H. Velders, P.J. Dijkstra, Z.Y. Zhong, X.S. Chen, J. Feijen, Chiral Salan Aluminum Ethyl Complexes and Their Application in Lactide Polymerization, Chem.-Eur. J. 2009, 15: 9836-9845.   8.pdf

    7. H.L. Sun, B.N. Guo, R. Cheng, F.H. Meng *, H.Y. Liu, Z.Y. Zhong*, Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin, Biomaterials  2009, 30: 6358-6366.   7.pdf

    6. W. Chen, F.H. Meng, F. Li, S.-J. Ji, Z.Y. Zhong*, pH-Responsive Biodegradable Micelles Based on Acid-Labile Polycarbonate Hydrophobe: Synthesis and Triggered Drug Release, Biomacromolecules 2009, 10: 1727-1735.   6.pdf

    5. H.F. Xu, F.H. Meng*, Z.Y. Zhong*, Reversibly crosslinked temperature-responsive nano-sized polymersomes: synthesis and triggered drug release, J. Mater. Chem. 2009, 19: 4183-4190.   5.pdf

    4. F.H. Meng, W.E.Hennink,  Z.Y. Zhong*, Reduction-Sensitive Polymers and Bioconjugates for Biomedical Applications, Biomaterials  2009, 30:2180-2198.   4.pdf

    3. R. Jin, L.S. Moreira Teixeira, P.J. Dijkstra, M. Karperien, Z.Y. Zhong, J. Feijen, Injectable Chitosan-based Hydrogels for Cartilage Tissue Engineering, Biomaterials 2009, 30:2544-2551   3.pdf

    2. H.Z. Du, A.H. Velders, P.J. Dijkstra, Z.Y. Zhong, X.S. Chen, J. Feijen, Polymerization of lactide using achiral bis(pyrrolidene) schiff base aluminum complexes, Macromolecules 2009, 42: 1058–1066.   2.pdf

    1. F.H. Meng, Z.Y. Zhong*, J. Feijen, Stimuli-responsive polymersomes for programmed drug delivery. Biomacromolecules 2009, 10: 197-209.   1.pdf


  • 1. 孟凤华,徐海飞,钟志远,界面交联的温度敏感的聚合物囊泡及其应用。授权专利号:ZL 2009 1 0030113.5. 授权公告日:2011年7月20日。

    2. 李玉玲,刘兆忠,周磊,孟凤华,钟志远,侧链用硫辛酸修饰的亲水性聚合物及其制备和应用。授权专利号:ZL 2009 1 0181922.6. 授权公告日:2011年9月28日。

    3. 朱彩虹,罗思彬,孟凤华,朱秀林,钟志远,生物可降解阳离子聚合物及其应用。授权专利号:ZL 2009 1 0232056.9. 授权公告日:2011年11月30日。

    4. 刘桂景,李少科,孟凤华,钟志远, 生物可降解聚合物囊泡及其制备和应用。授权专利号:ZL 2009 1 0264247.3. 授权公告日:2012年5月23日。

    5. 钟志远,刘兆忠,郑蒙,孟凤华,一种疏水基团修饰的聚乙烯亚胺衍生物及其应用。授权专利号:ZL 2011 1 0046746.2. 授权公告日:2012年12月5日。

    6. 钟志远, 李玉玲,刘兆忠,周磊,孟凤华,一种侧链用硫辛酸修饰的亲水性聚合物。授权专利号:ZL 2011 1 0110986.4.。授权公告日:2013年2月13日。

    7. 陈维,王荣,孟凤华,钟志远,含有丙烯酸酯类功能基团的环碳酸酯单体及其制备和应用。授权专利号:ZL 2009 1 0181912.2。授权公告日:2013年10月9日。

    8. 孟凤华,李少科,杨瑞,钟志远,一种双亲性聚合物构成的囊泡及其应用。授权专利号:ZL 2012 1 0158187.9。授权公告日:2014年4月1日。

    9. 钟志远,孟凤华,杜银锋,陈维,一种酸敏感可降解聚合物囊泡及其制备和应用。授权专利号:ZL 2012 1 0231361.8.。授权公告日:2014年10月30日。

    10. 孟凤华,顾裕丹,钟志远,一种酸敏感聚合物前药、其纳米粒及该纳米粒的应用,授权专利号:ZL 2013 1 0241009.7;授权公告日:2014年11月6日。

    11. 邓超,孟凤华,程茹,钟志远,乙烯砜取代的半胱氨酸-N-羧基内酸酐、其聚合物及聚合物的应用,授权专利号:2013 1 0206285.X;授权公告日:2015年3月25日。

    12. 邓超、范亚萍、孟凤华、程茹、钟志远,一种水凝胶、其制备方法及应用 ,江苏, 中华人民共和国国家产权局, 授权专利号:ZL 2013 1 0274019.0,授权公告日:2015年4月29日

    13. 孟凤华,邹艳,钟志远,含双硫五元环功能基团的环状碳酸酯单体及其制备方法,授权专利号: ZL 2014 1 0231697.3;专利申请日:2014年5月29日;授权公告日:2016年3月30日。

    14. 孟凤华,邹艳,钟志远,侧链含双硫五元环功能基团的碳酸酯聚合物及其应用,授权专利号: ZL 2014 1 0231049.8;专利申请日:2014年5月29日; 授权公告日:2016年9月7日。