2019
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2019


180Y. Yan, Y.Y. Dong, S.J. Yue, X.Y. Qiu, H.L. Sun*, and Z.Y. Zhong*, Dually Active Targeting Nanomedicines Based on a Direct Conjugate of Two Purely Natural Ligands for Potent Chemotherapy of Ovarian Tumor, ACS Appl. Mater. Interfaces 2019, 11, 46548-46557.180.pdf


179H.L. Sun, X.L. Gu, Q. Zhang, H. Xu, Z.Y. Zhong*, and C. Deng*, Cancer Nanomedicines Based on Synthetic Polypeptides, Biomacromolecules 2019, 20, 4299-4311.179.pdf


178L. Ding, W.X. Gu, Y.F. Zhang, S.J. Yue, H.L. Sun*, J. Cornelissen, and Z.Y. Zhong*, HER2-Specific Reduction-Sensitive Immunopolymersomes with High Loading of Epirubicin for Targeted Treatment of Ovarian Tumor,Biomacromolecules 2019, 20, 3855-3863.178.pdf


177Y. Zou, Y.H. Wei, J. Bao, F.R. Yao, Z.K. Li, Y.P. Sun, F.H. Meng*, C.H. Hu, G. Storm, and Z.Y. Zhong*, Cyclic RGD-Functionalized and Disulfide-Crosslinked Iodine-Rich Polymersomes as a Robust and Smart Theranostic Agent for Targeted CT Imaging and Chemotherapy of Melanoma, Theranostics 2019, 9, 8061-8072.177.pdf

  

176. W.X. Gu, J.N. An, H. Meng, N. Yu, Y.N. Zhong, F.H. Meng*, Y. Xu*, J.L.M. Cornelissen, and Z.Y. Zhong*, CD44-Specific A6 Short Peptide Boosts Targetability and Anticancer Efficacy of Polymersomal Epirubicin to Orthotopic Human Multiple Myeloma, Adv. Mater. 2019, 1904742.176.pdf

175.  X. Gu, Z. Zhu, Q. Fan, Y. Wei, G. Wang, F. Meng, Z. Zhong, C. Deng, Nanoagents based on poly(ethylene glycol)-b-poly(l-thyroxine) block copolypeptide for enhanced dual-modality imaging and targeted tumor radiotherapy. Small 2019, 0, 1902577.  175.pdf

174.  S. Cao, J. Shao, Y. Xia, H. Che, Z. Zhong, F. Meng, J. C. M. van Hest, L. K. E. A. Abdelmohsen, D. S. Williams, Molecular programming of biodegradable nanoworms via ionically induced morphology switch toward asymmetric therapeutic carriers. Small 2019, 15, 1901849. 174.pdf

173. H.L. Sun, Z.Y. Zhong*, and J. Feijen, The Fifth Symposium on Innovative Polymers for Controlled Delivery, September 14-17, 2018, Suzhou, China, J. Control. Release 2019, 307, 410-412.173.pdf

172. H.Z. Qin, Y. Jiang, J. Zhang, C. Deng*, and Z.Y. Zhong*, Oncoprotein Inhibitor Rigosertib Loaded in ApoE-Targeted Smart Polymersomes Reveals a High Safety and Potency against Human Glioblastoma in Mice, Mol. Pharmaceutics 2019, 16, 3711-3719.172.pdf

171. M. Qiu, J. Ouyang, Y.H. Wei, J. Zhang, Q. Lan, C. Deng*, and Z.Y. Zhong*, Selective cell penetrating peptide-functionalized envelope-type chimaeric lipopepsomes boost systemic RNAi therapy for lung tumor, Adv. Healthcare Mater. 2019, 1900500. 171.pdf

170. Y. Wei, X. Gu, L. Cheng, F. Meng, G. Storm, Z. Zhong, Low-toxicity transferrin-guided polymersomal doxorubicin for potent chemotherapy of orthotopic hepatocellular carcinoma in vivo. Acta Biomater. 2019, 92, 196-204.170.pdf

169.  K. Huang, Y. He, Z. Zhu, J. Guo, G. Wang, C. Deng, Z. Zhong, Small, traceable, endosome-disrupting, and bioresponsive click nanogels fabricated via microfluidics for CD44-targeted cytopla**ic delivery of therapeutic proteins. ACS Appl. Mater. Inter. 2019, 11, 22171-22180.169.pdf

168.  M. Qiu, J. Ouyang, Y. Wei, J. Zhang, Q. Lan, C. Deng, Z. Zhong, Selective cell penetrating peptide-functionalized envelope-type chimeric lipopepsomes boost systemic RNAi therapy for lung tumors. Adv. Healthcare Mater. 2019, 0, 1900500.168.pdf

167. J. S. Cao, Y. H. Wei, Y. X. Zhang, G. L. Wang, X. Ji, Z. Y. Zhong, Iodine-rich polymersomes enable versatile spect/ct imaging and potent radioisotope therapy for tumor in vivo. ACS Appl. Mater. Inter. 2019, 11, 18953-18959.167.pdf

166. X. Gu, Y. Wei, Q. Fan, H. Sun, R. Cheng, Z. Zhong, C. Deng, cRGD-decorated biodegradable polytyrosine nanoparticles for robust encapsulation and targeted delivery of doxorubicin to colorectal cancer in vivo. J. Control. Release 2019, 301, 110-118.166.pdf

165. D. Kuraitis, K. Hosoyama, N. J. R. Blackburn, C. Deng, Z. Zhong, E. J. Suuronen, Functionalization of soft materials for cardiac repair and regeneration. Crit. Rev. Biotechnol. 2019, 39, 451-468.165.pdf

164. S. Lecommandoux, H.-A. Klok, Z. Zhong, T. J. Deming, Future directions at the frontier of polymer science and biology. Biomacromolecules 2019, 20, 1-3.164.pdf

163. Q. Wang, Y. Zhong, W. Liu, Z. Wang, L. Gu, X. Li, J. Zheng, H. Du, Z. Zhong, F. Xie, Enhanced chemotherapeutic efficacy of the low-dose doxorubicin in breast cancer via nanoparticle delivery system crosslinked hyaluronic acid. Drug Deliv. 2019, 26, 12-22. 163.pdf

162. N. Rades, K. Achazi, M. Qiu, C. Deng, R. Haag, Z.Y. Zhong*, and K. Licha*, Reductively cleavable polymer-drug conjugates based on dendritic polyglycerol sulfate and monomethyl auristatin E as anticancer drugs, J. Control. Release 2019, 300, 13-21.162.pdf

161. X. Xu, W.J. Yang, Y.N. Shi, W.X. Zhang, X. Wang, F.H. Meng, and Z.Y. Zhong*, and L.C. Yin*, Efficient and Targeted Drug/siRNA Co-Delivery Mediated by Reversibly Crosslinked Polymersomes toward Anti-Inflammatory Treatment of Ulcerative Colitis (UC), Nano Res. 2019, 12, 659-667.161.pdf

160. J. Chen, H. He, C. Deng*, L.C. Yin, and Z.Y. Zhong*, Saporin-Loaded CD44 and EGFR Dual-Targeted Nanogels for Potent Inhibition of Metastatic Breast Cancer In Vivo, Int. J. Pharmaceutics 2019, 560, 57-64.160.pdf

159. P.L. Yao, Y.F. Zhang, H. Meng, H.L. Sun*, and Z.Y. Zhong*, Smart polymersomes dually functionalized with cRGD and fusogenic GALA peptides enable specific and high-efficiency cytosolic delivery of apoptotic proteins, Biomacromolecules 2019, 20, 184-191.159.pdf